pid-1 Antibody
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In Stock 
Product Specs
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
pid-1 antibody; F18A1.8 antibody; 21U-RNA biogenesis factor pid-1 antibody
Target Names
pid-1
Uniprot No.
Target Background
Function
This antibody targets pid-1, a component of the pid-1 variant of the PETISCO complex. This complex plays a crucial role in the biogenesis of a specific class of 21 nucleotide PIWI-interacting RNAs (piRNAs) known as 21U-RNAs, characterized by a uracil residue at their 5'-end. Pid-1 acts as an adapter within the complex, binding to it via erh-2. It is involved in the biogenesis of 21U-RNAs, which in turn guide the piwi protein prg-1 to its DNA targets for silencing. This process contributes to small RNA-directed transgenerational epigenetic inheritance.
Database Links
Subcellular Location
Cytoplasm. Nucleus. Cytoplasm, perinuclear region.
Tissue Specificity
Expressed predominantly in the germline (at protein level).
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