PLDGAMMA2 Antibody

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Product Specs

Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
PLDGAMMA2 antibody; At4g11830 antibody; T26M18.40 antibody; Phospholipase D gamma 2 antibody; AtPLDgamma2 antibody; PLD gamma 2 antibody; EC 3.1.4.4 antibody
Target Names
PLDGAMMA2
Uniprot No.

Target Background

Function
PLDGAMMA2 is an enzyme that hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond, generating phosphatidic acids (PA). It plays a significant role in diverse cellular processes, including phytohormone action, vesicular trafficking, secretion, cytoskeletal arrangement, meiosis, tumor promotion, pathogenesis, membrane deterioration, and senescence. While PLDGAMMA2 can utilize phosphatidylserine as a substrate, it exhibits a preference for ethanolamine-containing lipids. Notably, the enzyme can utilize phosphatidylcholine (PC) as a substrate in the presence of phosphatidylethanolamine (PE) and PIP2. PLDGAMMA2 is implicated in membrane lipid modulation under aluminum (Al) stress, and its elevated activity has been shown to negatively impact plant tolerance to Al.
Gene References Into Functions
  1. Research indicates that PLDgammas play a role in membrane lipid modulation under Al stress. Furthermore, elevated PLDgamma activities negatively impact plant tolerance to Al. PMID: 22163277
Database Links

KEGG: ath:AT4G11830

STRING: 3702.AT4G11830.2

UniGene: At.70227

Protein Families
Phospholipase D family, C2-PLD subfamily
Subcellular Location
Cytoplasm. Membrane; Peripheral membrane protein. Note=Found mainly associated with intracellular membranes but also with mitochondrial membranes, nuclei and clathrin-coated vesicles. Not found in chloroplast.
Tissue Specificity
Highly expressed in roots and flowers, moderately in stems, leaves and seedlings and low in siliques. Not detected in seeds.

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