PME19 Antibody

Possible Typographical Errors or Nomenclature Confusion

• PME-1 Antibody: The term "PME-1" (Protein Phosphatase Methylesterase 1) appears in [Source 11], which describes a demethylase involved in protein regulation. This antibody targets PPME1 and is associated with cancer research.

• PMEL Antibody: Multiple sources ( ) discuss PMEL (Premelanosome Protein), also known as gp100, a glycoprotein critical in melanosome formation and a target in melanoma research.

Antibodies with Similar Naming Conventions

The search results include antibodies targeting:

Relevant Antibody Classes and Structures

Antibodies such as IgM ( ) and IgG ( ) are structurally and functionally characterized in the sources. Key features include:

• IgM: Pentameric/hexameric structure with high avidity for antigens ( ).

• IgG: Monomeric structure with Fc-mediated effector functions ( ).

Therapeutic Antibody Development

Several antibodies in clinical use or trials are described, including:

• Anti-PD-1/PD-L1 antibodies: Used in cancer immunotherapy ( ).

• Anti-MERS-CoV antibodies: Neutralizing monoclonal antibodies for viral infections ( ).

Research Gaps and Recommendations

If "PME19 Antibody" is a novel or less-studied target, the following steps are advised:

1. Verify the correct nomenclature or target protein.

2. Explore databases like PubMed, ClinicalTrials.gov, or antibody-specific repositories for unpublished data.

3. Consider structural or functional homology with known antibodies (e.g., PME-1 or PMEL).