PNSB4 Antibody

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Description

Current Lack of Validated Data

  • No references to "PNSB4 Antibody" were identified in PubMed, PMC, or industry-standard antibody databases (e.g., Bio-Techne, Novus Biologicals) .

  • The abbreviation "PNS" commonly refers to the peripheral nervous system in medical literature, but no antibody designated "PNSB4" is associated with this terminology .

  • Antibody nomenclature typically follows standardized conventions (e.g., targeting antigen, species, or clone identifier), which further complicates validation of this designation.

Nomenclature Issues

  • The term may represent an internal or deprecated identifier from a non-public study.

  • Typographical errors or alternative naming conventions (e.g., "PN SB4" or "PNS-B4") could yield different results.

Research Stage

  • If "PNSB4" is a novel antibody under development, it may not yet be published or cataloged in public databases.

Recommendations for Further Inquiry

  1. Verify the Antibody Designation: Confirm the exact spelling, target antigen, or associated research context (e.g., neurological disorders, cancer).

  2. Explore Related Antibodies:

    • Neurofascin antibodies (e.g., NF155) are linked to autoimmune neuropathies .

    • Anti-myelin antibodies (e.g., PM43) target peripheral nervous system components .

    • α-synuclein antibodies (e.g., 5G4) are used in Parkinson’s disease research .

  3. Consult Specialized Databases:

    • PLAbDab (Patent and Literature Antibody Database) for unpublished sequences .

    • bNAber for broadly neutralizing antibodies (e.g., HIV research) .

Example Table: Antibodies with Similar Nomenclature

Antibody NameTarget AntigenAssociated ConditionKey FeaturesSource
PM43PNS myelin proteinDemyelination studiesIgM class, reacts with formalin-fixed tissue
NF155 IgG4Neurofascin-155Chronic inflammatory neuropathyFlow cytometry detection, IgG4 subclass
5G4α-synucleinParkinson’s diseaseConformation-specific, skin biopsy use

Next Steps

For researchers seeking information on "PNSB4 Antibody":

  • Contact antibody vendors (e.g., Bio-Techne, Novus Biologicals) for proprietary catalog inquiries.

  • Re-examine experimental protocols or collaborator communications for contextual clues.

  • Consider mass spectrometry or epitope binning to characterize unlabeled antibodies.

Product Specs

Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
PNSB4 antibody; NDF6 antibody; At1g18730 antibody; F6A14.16 antibody; Photosynthetic NDH subunit of subcomplex B 4 antibody; chloroplastic antibody; Protein PnsB4 antibody; NDH DEPENDENT FLOW 6 antibody; NDH-DEPENDENT CYCLIC ELECTRON FLOW 6 antibody
Target Names
PNSB4
Uniprot No.

Target Background

Function
The NDH complex functions as an electron shuttle, transferring electrons from NAD(P)H:plastoquinone to quinones in the photosynthetic chain and potentially in a chloroplast respiratory chain. The primary electron acceptor for this enzyme is believed to be plastoquinone. This process couples the redox reaction with proton translocation, effectively conserving the redox energy in a proton gradient.
Gene References Into Functions
  1. NDF6 is a novel subunit of the chloroplastic NDH complex, which was incorporated into terrestrial plants during evolutionary development. [NDF6] PMID: 18535009
Database Links

KEGG: ath:AT1G18730

STRING: 3702.AT1G18730.1

UniGene: At.43083

Subcellular Location
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.

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