POLR2I Antibody

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In Stock

Product Specs

Buffer
Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. Storage Temperature: -20°C. Avoid repeated freeze-thaw cycles.
Lead Time
Typically, we can ship your orders within 1-3 business days of receipt. Delivery times may vary depending on the purchasing method and location. For specific delivery times, please consult your local distributors.
Synonyms
DNA directed RNA polymerase II 14.5 kDa polypeptide antibody; DNA directed RNA polymerase II polypeptide I antibody; DNA directed RNA polymerase II subunit I antibody; DNA directed RNA polymerase II subunit RPB9 antibody; DNA-directed RNA polymerase II subunit I antibody; DNA-directed RNA polymerase II subunit RPB9 antibody; hRPB14.5 antibody; POLR2I antibody; Polymerase (RNA) II (DNA directed) polypeptide I 14.5kDa antibody; RNA polymerase II 14.5 kDa subunit antibody; RNA polymerase II subunit B9 antibody; RPB14.5 antibody; RPB9 antibody; RPB9_HUMAN antibody
Target Names
POLR2I
Uniprot No.

Target Background

Function
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. It is a component of RNA polymerase II, which synthesizes mRNA precursors and various functional non-coding RNAs. Pol II constitutes the core of the basal RNA polymerase II transcription machinery. Its structure comprises mobile elements that undergo relative movements. RPB9, positioned within the upper jaw encircling the central large cleft, is believed to bind the incoming DNA template.
Database Links

HGNC: 9196

OMIM: 180662

KEGG: hsa:5438

STRING: 9606.ENSP00000221859

UniGene: Hs.47062

Protein Families
Archaeal RpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family
Subcellular Location
Nucleus, nucleolus.

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