mig-6 Antibody
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In Stock 
Product Specs
Buffer
Preservative: 0.03% ProClin 300. Constituents: 50% Glycerol, 0.01M PBS, pH 7.4.
Form
Liquid
Lead Time
14-16 weeks (made-to-order)
Synonyms
mig-6 antibody; ppn-1 antibody; C37C3.6 antibody; Papilin antibody; Abnormal cell migration protein 6 antibody
Target Names
mig-6
Uniprot No.
Target Background
Function
MIG-6 is an extracellular matrix (ECM) protein with essential roles in several developmental processes. Specifically, it contributes to pharynx morphogenesis, likely through basement membrane remodeling. During embryogenesis, MIG-6 plays a crucial role in the second phase of distal cell tip migration and is necessary for the proper distribution of the metalloproteinase MIG-17 during organogenesis. Furthermore, MIG-6 is essential for post-embryonic distal cell tip migration and hypodermal enclosure in the developing embryo.
Database Links
Protein Families
Papilin family
Subcellular Location
Secreted, extracellular space, extracellular matrix, basement membrane.
Tissue Specificity
Localizes to the basement membranes of the gonad primordium, pharynx and intestine (at protein level). Expressed in head and CAN neurons, coelomocytes, body-wall muscles and anal depressor and sphincter and stomatointestinal muscles. Expressed Isoform a:
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