prde-1 Antibody

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Product Specs

Buffer
Preservative: 0.03% ProClin 300. Constituents: 50% Glycerol, 0.01M PBS, pH 7.4.
Form
Liquid
Lead Time
14-16 week lead time (made-to-order)
Synonyms
prde-1 antibody; F21A3.5 antibody; piRNA biogenesis factor prde-1 antibody; piRNA silencing defective protein 1 antibody
Target Names
prde-1
Uniprot No.

Target Background

Function
PRDE-1 is a nuclear factor essential for the biogenesis of piwi-interacting RNA (piRNA) precursors. Its function is particularly critical for piRNAs derived from loci containing the Ruby motif. PRDE-1 facilitates the recruitment of the transcription factor SNPC-4 to piRNA genomic clusters. Its presence is required for maintaining normal fertility.
Database Links

KEGG: cel:CELE_F21A3.5

STRING: 6239.F21A3.5

UniGene: Cel.36676

Subcellular Location
Nucleus. Chromosome.
Tissue Specificity
Expressed in male and female germ cells.

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