PRLHR Antibody
Shipped with Ice Packs 
In Stock 
Product Specs
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Lead Time
Typically, we can ship your orders within 1-3 business days of receipt. Delivery times may vary depending on the method of purchase and location. For specific delivery estimates, please consult your local distributor.
Synonyms
PRLHR; GPR10; GR3; Prolactin-releasing peptide receptor; PrRP receptor; PrRPR; G-protein coupled receptor 10; hGR3
Target Names
Uniprot No.
Target Background
Function
The PRLHR gene encodes the receptor for prolactin-releasing peptide (PrRP). This receptor is implicated in several physiological processes, including lactation, the regulation of food intake, and pain signal processing.
Gene References Into Functions
- Effects of systematic N-terminus deletions and benzoylations of endogenous RF-amide peptides on NPFF1R, NPFF2R, GPR10, GPR54 and GPR103. PMID: 26211894
- The "A/T" genotype of rs12413624 in the PRLHR gene has been associated with a decreased risk of colorectal cancer. PMID: 26302849
- Research has demonstrated previously unrecognized roles for GPR10 and its upstream regulator REST in the pathogenesis of uterine fibroids. PMID: 23284171
- Structural analysis has been conducted on the human PrRP receptor (PrRPR) and the ligand-mimicking receptor variant of prolactin-releasing peptide. PMID: 22778259
- The human PrRP receptor gene (PRL-releasing peptide receptor; PrRPR) and its promoter region have been cloned and characterized. PMID: 11923475
- Due to its high expression in tumor tissue, the PrRP receptor likely plays a role in pheochromocytomas. PMID: 12126742
- The neuron-restrictive silencer factor confers transcriptional repression of the GPR10 gene via a putative silencer element located in the 5' promoter region. PMID: 12417311
- Studies have indicated an association of polymorphisms in this gene with blood pressure, but not obesity, in a U.K. Caucasian population. PMID: 12716769
- The rat orphan receptor UHR-1 has been identified as a ligand for this receptor. PMID: 15752583
Database Links
Protein Families
G-protein coupled receptor 1 family
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Tissue Specificity
Only detected in the pituitary gland and in all cell types of pituitary adenomas.
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