HDAC2 Polyclonal Antibody Antibodies
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HDAC2 Polyclonal Antibody

The product is for non-human research only. Not for therapeutic or veterinary use.

Catalog No: bt-227770

Product Name HDAC2 Polyclonal Antibody
Application WB;IHC
Application Key Western blotting
Calculated Mw 51kDa/55kDa
Cellular Location Cytoplasm,Nucleus
Customer Validation WB (Human)
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 429-488 of human HDAC2 (NP_001518.3).
Isotype IgG
Observed Mw 54kDa
Product Background This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.
Positive Samples NCI-H460
Purification Method Affinity purification
Recommended Dilution WB
Reference Product: HDAC2 Polyclonal Antibody
Journal: Neuroscience
Application: WB
IF: 3.276
Species: Human
PMID: 25779965
Title: Galangin-induced down-regulation of BACE1 by epigenetic mechanisms in SH-SY5Y cells

Product: HDAC2 Polyclonal Antibody
Journal: Nucleic acids research
Application: WB
IF: 10.032
Species: Human
PMID: 29190394
Title: Acetylation of 53BP1 dictates the DNA double strand break repair pathway
Sequence EGGRRNVADHKKGAKKARIEEDKKETEDKKTDVKEEDKSKDNSGEKTDTKGTKSEQLSNP
Species Reactivity Human, Mouse, Rat
Storage Buffer Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.