TGFB1 Monoclonal Antibody
The product is for non-human research only. Not for therapeutic or veterinary use.
Catalog Number: BT-228283
| Product Name | TGFB1 Monoclonal Antibody |
|---|---|
| Application | WB;FC |
| Application Key | Western blotting |
| Calculated Mw | 44kDa |
| Cellular Location | Secreted,extracellular matrix,extracellular space |
| Customer Validation | IHC (Human)WB (Human) |
| Host Species | Mouse |
| Immunogen | Recombinant protein of human TGFB1 |
| Isotype | IgG |
| Observed Mw | 40kDa |
| Product Background | This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease. |
| Positive Samples | A-549,HepG2 |
| Purification Method | Affinity purification |
| Recommended Dilution | WB |
| Reference | Product: TGFB1 Monoclonal Antibody Journal: Scientific Reports Application: IHC IF: 4.258 Species: Human PMID: 24966004 Title: Disorganized vascular structures in sporadic venous malformations Product: TGFB1 Monoclonal Antibody Journal: European Journal of Pharmaceutical Sciences Application: IHC IF: 3.756 Species: Human PMID: 28104472 Title: Downregulation of miR-145 in venous malformations Product: TGFB1 Monoclonal Antibody Journal: Toxicology in Vitro Application: WB IF: 3.1 Species: Human PMID: 29928970 Title: Gallic acid-coated sliver nanoparticle alters the expression of radiation-induced epithelial-mesenchymal transition in non-small lung cancer cells. |
| Sequence | Email for sequence |
| Species Reactivity | Human |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Last Modified | Aug 20 2021 |