TGFB1 Monoclonal Antibody Antibodies
$ $99 In stock

TGFB1 Monoclonal Antibody

Catalog Number bt-228283
Product Name TGFB1 Monoclonal Antibody
Product Type
Host Species Mouse
Species Reactivity Human
isotype IgG
Application WB;FC
Product Background This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.
Reference Array
Immunogen Recombinant protein of human TGFB1
Sequence Email for sequence
Customer Validation IHC (Human)WB (Human)
Recommended Dilution WB
Calculated MW 44kDa
Observed MW 40kDa
Storage Buffer Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Key Western blotting
Positive Samples A-549,HepG2
Cellular Location Secreted,extracellular matrix,extracellular space
Purification Method Affinity purification
RRID AB_2757103