TGFB1 Monoclonal Antibody Antibodies
$ $99 In stock
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TGFB1 Monoclonal Antibody

The product is for non-human research only. Not for therapeutic or veterinary use.

Catalog No: bt-228283

Product Name TGFB1 Monoclonal Antibody
Application WB;FC
Application Key Western blotting
Calculated Mw 44kDa
Cellular Location Secreted,extracellular matrix,extracellular space
Customer Validation IHC (Human)WB (Human)
Host Species Mouse
Immunogen Recombinant protein of human TGFB1
Isotype IgG
Observed Mw 40kDa
Product Background This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.
Positive Samples A-549,HepG2
Purification Method Affinity purification
Recommended Dilution WB
Reference Product: TGFB1 Monoclonal Antibody
Journal: Scientific Reports
Application: IHC
IF: 4.258
Species: Human
PMID: 24966004
Title: Disorganized vascular structures in sporadic venous malformations

Product: TGFB1 Monoclonal Antibody
Journal: European Journal of Pharmaceutical Sciences
Application: IHC
IF: 3.756
Species: Human
PMID: 28104472
Title: Downregulation of miR-145 in venous malformations

Product: TGFB1 Monoclonal Antibody
Journal: Toxicology in Vitro
Application: WB
IF: 3.1
Species: Human
PMID: 29928970
Title: Gallic acid-coated sliver nanoparticle alters the expression of radiation-induced epithelial-mesenchymal transition in non-small lung cancer cells.
Sequence Email for sequence
Species Reactivity Human
Storage Buffer Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Last Modified Mar 08 2019