SDHA Polyclonal Antibody
The product is for non-human research only. Not for therapeutic or veterinary use.
Catalog No: bt-228496
| Product Name | SDHA Polyclonal Antibody |
|---|---|
| Application | WB;IHC;IF |
| Application Key | Western blotting |
| Calculated Mw | 56kDa/67kDa/72kDa |
| Cellular Location | Matrix side,Mitochondrion inner membrane,Peripheral membrane protein |
| Customer Validation | WB (Human) |
| Host Species | Rabbit |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 385-664 of human SDHA (NP_004159.2). |
| Isotype | IgG |
| Observed Mw | 70kDa |
| Product Background | This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Positive Samples | HepG2,U-251MG,PC-3,MCF7,Mouse liver,Mouse stomach,NCI-H125 |
| Purification Method | Affinity purification |
| Recommended Dilution | WB |
| Sequence | ETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVLRHVNGQDQIVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIEESCRPGDKVPPIKPNAGEESVMNLDKLRFADGSIRTSELRLSMQKSMQNHAAVFRVGSVLQEGCGKISKLYGDLKHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKVRIDEYDYSKPIQGQQKKPFEEHWRKHTLSYVDVGTGKVTLEYRPVIDKTLNEADCATVPPAIRSY |
| Species Reactivity | Human, Mouse, Rat |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |