PRKAB1 Monoclonal Antibody Antibodies
$ $99 In stock

PRKAB1 Monoclonal Antibody

Product Name PRKAB1 Monoclonal Antibody
Product Type
Host Species Mouse
Species Reactivity Human, Mouse, Rat, Monkey
isotype IgG
Application WB;IHC;ICC;IP
Product Background The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.
Immunogen Recombinant protein of human PRKAB1
Sequence Email for sequence
Recommended Dilution WB
Calculated MW 30kDa
Observed MW 38kDa
Storage Buffer Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Key Western blotting
Positive Samples HeLa,PC-12,SH-SY5Y,NCI-H460,Jurkat,NIH/3T3,Mouse pancreas
Purification Method Affinity purification
RRID AB_2757426