EIF4G1 Polyclonal Antibody Antibodies
$ $99 In stock

EIF4G1 Polyclonal Antibody

Product Name EIF4G1 Polyclonal Antibody
Product Type
Host Species Rabbit
Species Reactivity Human, Mouse, Rat
isotype IgG
Application WB;IHC;IF;IP
Product Background The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage.
Immunogen Recombinant protein of human EIF4G1
Sequence Email for sequence
Recommended Dilution WB
Calculated MW 154kDa/158kDa/166kDa/171kDa/175kDa/176kDa
Observed MW 250kDa
Storage Buffer Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Key Western blotting
Positive Samples HeLa,NIH/3T3,PC-12
Purification Method Affinity purification
RRID AB_2757439