ITGA6 Monoclonal Antibody Antibodies
$ $99 In stock

ITGA6 Monoclonal Antibody

The product is for non-human research only. Not for therapeutic or veterinary use.

Catalog No: bt-235698

Product Name ITGA6 Monoclonal Antibody
Application WB;IHC;IF;FC
Application Key Western blotting
Calculated Mw 106kDa/119kDa/121kDa/122kDa/124kDa/126kDa
Cellular Location Cell membrane,Lipid-anchor,Single-pass type I membrane protein
Host Species Mouse
Immunogen A synthetic peptide of human ITGA6
Isotype IgG
Observed Mw 130kDa
Product Background The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants.
Positive Samples HepG2
Purification Method Affinity purification
Recommended Dilution WB
Sequence Email for sequence
Species Reactivity Human
Storage Buffer Store at 4℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, pH7.3.