ERK2 Polyclonal Antibody
The product is for non-human research only. Not for therapeutic or veterinary use.
Catalog No: bt-235706
| Product Name | ERK2 Polyclonal Antibody |
|---|---|
| Application | WB;IHC;FC |
| Application Key | Western blotting |
| Calculated Mw | 36kDa/41kDa |
| Cellular Location | Cytoplasm,Nucleus,centrosome,cytoskeleton,microtubule organizing center,spindle |
| Host Species | Rabbit |
| Immunogen | A synthetic peptide of human ERK2 |
| Isotype | IgG |
| Observed Mw | 41kDa |
| Product Background | This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. |
| Positive Samples | HeLa |
| Purification Method | Affinity purification |
| Recommended Dilution | WB |
| Sequence | Email for sequence |
| Species Reactivity | Human |
| Storage Buffer | Store at 4℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, pH7.3. |