HLA-F Polyclonal Antibody Antibodies
$ $99 In stock

HLA-F Polyclonal Antibody

The product is for non-human research only. Not for therapeutic or veterinary use.

Catalog No: bt-235849

Product Name HLA-F Polyclonal Antibody
Application WB;FC
Application Key Western blotting
Calculated Mw 28kDa/39kDa/50kDa
Cellular Location Membrane,Single-pass type I membrane protein
Host Species Rabbit
Immunogen A synthetic peptide of human HLA-F
Isotype IgG
Observed Mw 34kDa
Product Background This gene belongs to the HLA class I heavy chain paralogues. It encodes a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation. This gene exhibits few polymorphisms. Multiple transcript variants encoding different isoforms have been found for this gene. These variants lack a coding exon found in transcripts from other HLA paralogues due to an altered splice acceptor site, resulting in a shorter cytoplasmic domain.
Positive Samples HL-60
Purification Method Affinity purification
Recommended Dilution WB
Sequence Email for sequence
Species Reactivity Human
Storage Buffer Store at 4℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, pH7.3.