TMED10 Polyclonal Antibody Antibodies
$ $99 In stock
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TMED10 Polyclonal Antibody

The product is for non-human research only. Not for therapeutic or veterinary use.

Catalog No: bt-237492

Product Name TMED10 Polyclonal Antibody
Application WB;IHC;IF
Application Key Western blotting
Calculated Mw 24kDa
Cellular Location Cell membrane,Cytoplasmic vesicle,Endoplasmic reticulum membrane,Endoplasmic reticulum-Golgi intermediate compartment membrane,Golgi apparatus,Melanosome,Single-pass type I membrane protein,cis-Golgi network membrane,secretory vesicle membrane,trans-Golgi
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 35-190 of human TMED10 (NP_006818.3).
Isotype IgG
Observed Mw 21kDa
Product Background This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.
Positive Samples Raji,HeLa,MCF7,Mouse lung,Rat lung
Purification Method Affinity purification
Recommended Dilution WB
Sequence HLPINSRKCLREEIHKDLLVTGAYEISDQSGGAGGLRSHLKITDSAGHILYSKEDATKGKFAFTTEDYDMFEVCFESKGTGRIPDQLVILDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFS
Species Reactivity Human, Mouse, Rat
Storage Buffer Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.