Phospho-SNCA-Y136 pAb Antibodies
$ $99 In stock

Phospho-SNCA-Y136 pAb

The product is for non-human research only. Not for therapeutic or veterinary use.

Catalog No: bt-239712

Product Name Phospho-SNCA-Y136 pAb
Application WB;IF
Application Key Western blotting
Calculated Mw 11kDa/13kDa/14kDa
Cellular Location Cell junction,Cytoplasm,Membrane,Nucleus,Secreted,cytosol,synapse
Host Species Rabbit
Immunogen A phospho specific peptide corresponding to residues surrounding Y136 of human SNCA
Isotype IgG
Observed Mw 17kDa
Product Background Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.
Positive Samples Mouse brain
Purification Method Affinity purification
Recommended Dilution WB
Sequence Email for sequence
Species Reactivity Human, Mouse, Rat
Storage Buffer Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.