Phospho-Rb-S807/811 pAb Antibodies
$ $99 In stock
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Phospho-Rb-S807/811 pAb

The product is for non-human research only. Not for therapeutic or veterinary use.

Catalog No: bt-239865

Product Name Phospho-Rb-S807/811 pAb
Application WB
Application Key Western blotting
Calculated Mw 106kDa
Cellular Location Nucleus
Host Species Rabbit
Immunogen A synthetic phosphorylated peptide around S807 & S811 of human Rb (NP_000312.2).
Isotype IgG
Observed Mw 120kDa
Product Background The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.
Positive Samples HT-29
Purification Method Affinity purification
Recommended Dilution WB
Sequence SPLKS
Species Reactivity Human
Storage Buffer Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Last Modified Mar 08 2019