Phospho-TrkA-Y490 pAb Antibodies
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Phospho-TrkA-Y490 pAb

The product is for non-human research only. Not for therapeutic or veterinary use.

Catalog No: bt-239870

Product Name Phospho-TrkA-Y490 pAb
Application WB
Application Key Western blotting
Calculated Mw 77kDa/83kDa/86kDa/87kDa
Cellular Location Cell membrane,Early endosome membrane,Late endosome membrane,Single-pass type I membrane protein
Host Species Rabbit
Immunogen A phospho specific peptide corresponding to residues surrounding Y490 of human TrkA
Isotype IgG
Observed Mw 150kDa
Product Background This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
Positive Samples NIH/3T3
Purification Method Affinity purification
Recommended Dilution WB
Sequence Email for sequence
Species Reactivity Human, Mouse
Storage Buffer Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Last Modified Mar 08 2019