Recombinant MERS-CoV (NCoV / Novel coronavirus) Spike Protein fragment (aa 367-606, Fc Tag) Antigens The spike protein fragment (Human betacoronavirus 2c EMC/2012)(AFS88936.1) (Glu367-Tyr606) was fused with the Fc region of rabbit IgG at the C-terminus. The recombinant spike protein fragment (Human betacoronavirus 2c EMC/2012) comprises 46.4a.a and has a predicted molecular weight of 51.5 kDa. It migrates as an approximately 54.3 kDa band in SDS-PAGE under reducing conditions.
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Formulation: The recombinant spike protein fragment (Human betacoronavirus 2c EMC/2012) comprises 46.4a.a and has a predicted molecular weight of 51.5 kDa. It migrates as an approximately 54.3 kDa band in SDS-PAGE under reducing conditions.
Source: Baculovirus-Insect Cells
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use.

Recombinant MERS-CoV (NCoV / Novel coronavirus) Spike Protein fragment (aa 367-606, Fc Tag)

Formulation: Recombinant MERS-CoV (NCoV / Novel coronavirus) Spike Protein was lyophilized from sterile 100 mM Glycine, 10 mM NaCl, pH 7.2.1.

Source: Baculovirus-Insect Cells

Product Name Recombinant MERS-CoV (NCoV / Novel coronavirus) Spike Protein fragment (aa 367-606, Fc Tag)
Product Type Antigen
Source Baculovirus-Insect Cells
Formulation Recombinant MERS-CoV (NCoV / Novel coronavirus) Spike Protein was lyophilized from sterile 100 mM Glycine, 10 mM NaCl, pH 7.2.1.
Molecular Weight The recombinant spike protein fragment (Human betacoronavirus 2c EMC/2012) comprises 46.4a.a and has a predicted molecular weight of 51.5 kDa. It migrates as an approximately 54.3 kDa band in SDS-PAGE under reducing conditions.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Purity Greater than 80% as determined by SDS-PAGE
Description The spike protein fragment (Human betacoronavirus 2c EMC/2012)(AFS88936.1) (Glu367-Tyr606) was fused with the Fc region of rabbit IgG at the C-terminus.
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use.
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
AA Sequence Glu367-Tyr606
Product Background The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell: they are essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of heterologous proteins on the virus surface that function together. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. The SARS-CoV spike (S) protein is composed of two subunits; the S1 subunit contains a receptor-binding domain that engages with the host cell receptor angiotensin-converting enzyme 2 and the S2 subunit mediates fusion between the viral and host cell membranes. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity, during infection with SARS-CoV.
Memo S Protein, MERS-CoV
Terminal Glu 367
Bioactivity Please contact us for detailed information