Recombinant Influenza A H1N1 (A/NewJersey/8/1976) Hemagglutinin / HA1 Protein (His Tag)
The product is for non-human research only. Not for therapeutic or veterinary use.
Catalog No: bt-224555
Molecular Weight: The recombinant HA1 subunit of the (A/NewJersey/8/1976 (H1N1)) hemagglutinin consists 338a.a and predicts a molecular weight of 37.7 kDa.
Formulation: Recombinant Influenza A H1N1 (A/NewJersey/8/1976) Hemagglutinin / HA1 Protein was lyophilized from sterile PBS, pH 7.4.1.
Source: HEK293 Cells
|Product Name||Recombinant Influenza A H1N1 (A/NewJersey/8/1976) Hemagglutinin / HA1 Protein (His Tag)|
|Molecular Weight||The recombinant HA1 subunit of the (A/NewJersey/8/1976 (H1N1)) hemagglutinin consists 338a.a and predicts a molecular weight of 37.7 kDa.|
|Bioactivity||Please contact us for detailed information|
|Endotoxin||< 1.0 EU per μg protein as determined by the LAL method.|
|Formulation||Recombinant Influenza A H1N1 (A/NewJersey/8/1976) Hemagglutinin / HA1 Protein was lyophilized from sterile PBS, pH 7.4.1.|
|Description||The Influenza A virus (A/NewJersey/8/1976 (H1N1)) hemagglutinin (ACU80014.1) (Met1-Arg344), termed as HA1, was expressed with a polyhistidine tag at the C-terminus.|
|Product Background||The influenza viral Hemagglutinin (HA) protein is a homo trimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two functions. Firstly, it allows the recognition of target vertebrate cells, accomplished through the binding to these cells' sialic acid-containing receptors. Secondly, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of host endosomal membrane with the viral membrane.The influenza virus Hemagglutinin (HA) protein is translated in cells as a single protein, HA, or hemagglutinin precursor protein. For viral activation, hemagglutinin precursor protein (HA) must be cleaved by a trypsin-like serine endoprotease at a specific site, normally coded for by a single basic amino acid (usually arginine) between the HA1 and HA2 domains of the protein. After cleavage, the two disulfide-bonded protein domains produce the mature form of the protein subunits as a prerequisite for the conformational change necessary for fusion and hence viral infectivity.|
|Purity||Greater than 90% as determined by SDS-PAGE.|
|Storage||Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.|
|Usage||Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use.|
|Last Modified||Mar 08 2019|