FGG Polyclonal Antibody
The product is for non-human research only. Not for therapeutic or veterinary use.
Catalog Number: BT-236707
| Product Name | FGG Polyclonal Antibody |
|---|---|
| Application | WB;IF |
| Application Key | Western blotting |
| Calculated Mw | 49kDa/51kDa |
| Cellular Location | Secreted |
| Host Species | Rabbit |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 50-330 of human FGG (NP_000500.2). |
| Isotype | IgG |
| Observed Mw | 53kDa |
| Product Background | The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in transcript variants encoding different isoforms. |
| Positive Samples | SGC-996,Mouse liver,Mouse lung |
| Purification Method | Affinity purification |
| Recommended Dilution | WB |
| Sequence | GIADFLSTYQTKVDKDLQSLEDILHQVENKTSEVKQLIKAIQLTYNPDESSKPNMIDAATLKSRKMLEEIMKYEASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFF |
| Species Reactivity | Human, Mouse |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Last Modified | Jul 26 2021 |