Z-Tyr-OtBu - 16881-33-7

Z-Tyr-OtBu

Catalog Number: EVT-247568
CAS Number: 16881-33-7
Molecular Formula:
Molecular Weight: 371.4
The product is for non-human research only. Not for therapeutic or veterinary use.
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Product Introduction

Description
Z-Tyr-OtBu is a synthetic peptide that has gained significant attention in the scientific community due to its potential therapeutic and industrial applications. This paper aims to provide a comprehensive review of Z-Tyr-OtBu, including its method of synthesis or extraction, chemical structure and biological activity, biological effects, applications, future perspectives, and challenges.
Applications in Various Fields
Z-Tyr-OtBu has potential applications in medical research, environmental research, and industrial research. In medical research, Z-Tyr-OtBu can be used in drug development and clinical trials to determine its efficacy and safety as a therapeutic agent. In environmental research, Z-Tyr-OtBu can be used to study its effects on ecosystems and its role in pollution management. In industrial research, Z-Tyr-OtBu can be used in manufacturing processes to improve product quality and efficiency. However, the use of Z-Tyr-OtBu in industrial research requires careful consideration of health and safety considerations.

Properties

CAS Number

16881-33-7

Product Name

Z-Tyr-OtBu

IUPAC Name

tert-butyl (2S)-3-(4-hydroxyphenyl)-2-(phenylmethoxycarbonylamino)propanoate

Molecular Weight

371.4

InChI

InChI=1S/C21H25NO5/c1-21(2,3)27-19(24)18(13-15-9-11-17(23)12-10-15)22-20(25)26-14-16-7-5-4-6-8-16/h4-12,18,23H,13-14H2,1-3H3,(H,22,25)/t18-/m0/s1

SMILES

CC(C)(C)OC(=O)C(CC1=CC=C(C=C1)O)NC(=O)OCC2=CC=CC=C2
Method of Synthesis or Extraction
Z-Tyr-OtBu can be synthesized using various methods, including solid-phase peptide synthesis (SPPS), solution-phase peptide synthesis, and chemical synthesis. SPPS is the most commonly used method for synthesizing Z-Tyr-OtBu due to its efficiency and yield. However, SPPS requires the use of toxic solvents and reagents, which can have adverse environmental and safety considerations. Solution-phase peptide synthesis and chemical synthesis are alternative methods that can be used to synthesize Z-Tyr-OtBu. These methods are less efficient than SPPS but have fewer environmental and safety considerations.
Chemical Structure and Biological Activity
Z-Tyr-OtBu has a chemical structure of Z-Tyr-OtBu (benzyloxycarbonyl-L-tyrosine tert-butyl ester). It is a synthetic peptide that has been shown to have potent biological activity. Z-Tyr-OtBu acts as a proteasome inhibitor, which inhibits the degradation of proteins in cells. This mechanism of action makes Z-Tyr-OtBu a potential therapeutic agent for the treatment of cancer and other diseases.
Biological Effects
Z-Tyr-OtBu has been shown to have significant effects on cell function and signal transduction. It has been shown to induce apoptosis (programmed cell death) in cancer cells, which makes it a potential therapeutic agent for the treatment of cancer. However, Z-Tyr-OtBu can also have toxic effects on healthy cells, which can limit its therapeutic potential. Further research is needed to determine the potential therapeutic and toxic effects of Z-Tyr-OtBu.
Future Perspectives and Challenges
The use of Z-Tyr-OtBu in scientific research is still in its early stages, and there are several limitations and challenges that need to be addressed. One of the main challenges is the potential toxic effects of Z-Tyr-OtBu on healthy cells, which can limit its therapeutic potential. Further research is needed to determine the optimal dosage and administration of Z-Tyr-OtBu to minimize its toxic effects. Another challenge is the environmental and safety considerations associated with the synthesis and use of Z-Tyr-OtBu. Future research should focus on developing more sustainable and environmentally friendly methods for synthesizing and using Z-Tyr-OtBu.
Conclusion
In conclusion, Z-Tyr-OtBu is a synthetic peptide that has significant potential in medical, environmental, and industrial research. Its mechanism of action as a proteasome inhibitor makes it a potential therapeutic agent for the treatment of cancer and other diseases. However, further research is needed to determine its potential therapeutic and toxic effects, as well as its environmental and safety considerations. The use of Z-Tyr-OtBu in scientific research requires careful consideration of its limitations and challenges, as well as its potential benefits and applications.

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