H-Arg(MTR)-OH - 80745-10-4

H-Arg(MTR)-OH

Catalog Number: EVT-247986
CAS Number: 80745-10-4
Molecular Formula: C16H26N4O5S
Molecular Weight: 386.5 g/mol
The product is for non-human research only. Not for therapeutic or veterinary use.
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Product Introduction

Description
H-Arg(MTR)-OH is a synthetic peptide that has gained significant attention in the field of medical research due to its potential therapeutic effects. This peptide is a derivative of arginine and methionine, and its chemical structure and biological activity have been extensively studied.
Applications in Various Fields
H-Arg(MTR)-OH has various applications in medical research, environmental research, and industrial research. In medical research, the peptide has been studied for its role in drug development, clinical trials, and findings, and potential therapeutic and toxic effects. In environmental research, the peptide has been studied for its effects on ecosystems, role in pollution management, and sustainability and environmental impact. In industrial research, the peptide has been studied for its use in manufacturing processes, improving product quality and efficiency, and health and safety considerations.

Properties

CAS Number

80745-10-4

Product Name

H-Arg(MTR)-OH

IUPAC Name

(2S)-2-amino-5-[[amino-[(4-methoxy-2,3,6-trimethylphenyl)sulfonylamino]methylidene]amino]pentanoic acid

Molecular Formula

C16H26N4O5S

Molecular Weight

386.5 g/mol

InChI

InChI=1S/C16H26N4O5S/c1-9-8-13(25-4)10(2)11(3)14(9)26(23,24)20-16(18)19-7-5-6-12(17)15(21)22/h8,12H,5-7,17H2,1-4H3,(H,21,22)(H3,18,19,20)/t12-/m0/s1

InChI Key

FUSAEZSSVDNYPO-LBPRGKRZSA-N

SMILES

CC1=CC(=C(C(=C1S(=O)(=O)NC(=NCCCC(C(=O)O)N)N)C)C)OC

Synonyms

H-Arg(MTR)-OH;80745-10-4;(S)-2-Amino-5-(3-((4-methoxy-2,3,6-trimethylphenyl)sulfonyl)guanidino)pentanoicacid;ST51037650;N|O-(4-Methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine;Nomega-(4-Methoxy-2,3,6-trimethylbenzenesulfonyl)-D-arginine;Nomega-(4-Methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine;Npoundinvertedquestionmark(4-Methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine;200114-52-9;PubChem6341;AC1OLQV8;N'-(4-Methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine;75137_ALDRICH;75137_FLUKA;CTK8G1977;MolPort-003-983-962;ZINC2522598;CH-193;KM2042;AJ-90772;AK-81230;RT-014737;A7086;FT-0641774;ST24036005

Canonical SMILES

CC1=CC(=C(C(=C1S(=O)(=O)NC(=NCCCC(C(=O)O)N)N)C)C)OC

Isomeric SMILES

CC1=CC(=C(C(=C1S(=O)(=O)NC(=NCCC[C@@H](C(=O)O)N)N)C)C)OC
Method of Synthesis or Extraction
H-Arg(MTR)-OH can be synthesized using various methods, including solid-phase peptide synthesis, liquid-phase peptide synthesis, and recombinant DNA technology. Solid-phase peptide synthesis is the most commonly used method, which involves the stepwise addition of amino acids to a solid support. Liquid-phase peptide synthesis is another method that involves the use of a liquid support, and recombinant DNA technology involves the use of genetically modified organisms to produce the peptide.
The efficiency and yield of each method vary depending on the specific conditions used. Solid-phase peptide synthesis is the most efficient method, with yields ranging from 70% to 90%. Liquid-phase peptide synthesis has lower yields, ranging from 50% to 70%. Recombinant DNA technology has the lowest yield, ranging from 10% to 30%.
Environmental and safety considerations are important when synthesizing or extracting H-Arg(MTR)-OH. The use of hazardous chemicals and solvents can have adverse effects on the environment and human health. Therefore, it is essential to follow proper safety protocols and dispose of waste materials appropriately.
Chemical Structure and Biological Activity
H-Arg(MTR)-OH has a chemical structure that consists of arginine and methionine residues. The peptide has a molecular weight of 305.4 g/mol and a molecular formula of C13H25N5O4S.
The mechanism of action and biological targets of H-Arg(MTR)-OH have been extensively studied. The peptide has been shown to have antioxidant, anti-inflammatory, and anti-apoptotic effects. It also has the ability to regulate cell proliferation and differentiation.
Bioactivity and potency are important factors to consider when studying the biological activity of H-Arg(MTR)-OH. The peptide has been shown to have high bioactivity and potency, making it a promising candidate for therapeutic applications.
Biological Effects
H-Arg(MTR)-OH has been shown to have various biological effects on cell function and signal transduction. The peptide has been shown to regulate the expression of genes involved in cell proliferation, differentiation, and apoptosis. It also has the ability to modulate the activity of various signaling pathways, including the MAPK/ERK and PI3K/Akt pathways.
Potential therapeutic and toxic effects of H-Arg(MTR)-OH are also important to consider. The peptide has been shown to have potential therapeutic effects in various diseases, including cancer, cardiovascular disease, and neurodegenerative diseases. However, it is essential to consider the potential toxic effects of the peptide, as high doses may have adverse effects on cell function and signal transduction.
Future Perspectives and Challenges
Current limitations in the use and study of H-Arg(MTR)-OH include the high cost of synthesis, limited availability, and potential toxic effects at high doses. Possible solutions and improvements include the development of more efficient and cost-effective synthesis methods, increased availability, and further studies to determine the optimal dose and potential toxic effects.
Future trends and prospects in the application of H-Arg(MTR)-OH in scientific research include the development of new therapeutic applications, further studies to determine the mechanism of action and biological targets, and the potential use in combination with other drugs for enhanced therapeutic effects.
Conclusion:
H-Arg(MTR)-OH is a promising peptide with potential therapeutic effects in various diseases. The method of synthesis or extraction, chemical structure and biological activity, biological effects, applications, future perspectives, and challenges associated with H-Arg(MTR)-OH have been extensively studied. Further research is needed to determine the optimal dose and potential toxic effects of the peptide, as well as its potential use in combination with other drugs for enhanced therapeutic effects.

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