2-Amino-6-(1-aminoethylideneamino)hexanoic acid - 53774-63-3

2-Amino-6-(1-aminoethylideneamino)hexanoic acid

Catalog Number: EVT-248528
CAS Number: 53774-63-3
Molecular Formula: C8H17N3O2
Molecular Weight: 187.24
The product is for non-human research only. Not for therapeutic or veterinary use.
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Product Introduction

Description
2-Amino-6-(1-aminoethylideneamino)hexanoic acid, also known as L-homoserine, is a non-proteinogenic amino acid that is commonly found in bacteria and plants. It is a precursor to threonine, an essential amino acid in humans. L-homoserine has been studied for its potential therapeutic and industrial applications, as well as its effects on the environment.
Applications in Various Fields
In medical research, 2-Amino-6-(1-aminoethylideneamino)hexanoic acid has been studied for its role in drug development and clinical trials. It has been investigated as a potential treatment for various conditions, including cancer and neurodegenerative diseases. However, its use in humans is limited due to its potential toxicity. In environmental research, 2-Amino-6-(1-aminoethylideneamino)hexanoic acid has been studied for its effects on ecosystems and its role in pollution management. It has been shown to have both positive and negative impacts on the environment, depending on the context. In industrial research, 2-Amino-6-(1-aminoethylideneamino)hexanoic acid has been used in manufacturing processes to improve product quality and efficiency. Health and safety considerations must be taken into account when using 2-Amino-6-(1-aminoethylideneamino)hexanoic acid in industrial settings.

Properties

CAS Number

53774-63-3

Product Name

2-Amino-6-(1-aminoethylideneamino)hexanoic acid

IUPAC Name

2-amino-6-(1-aminoethylideneamino)hexanoic acid

Molecular Formula

C8H17N3O2

Molecular Weight

187.24

InChI

InChI=1S/C8H17N3O2/c1-6(9)11-5-3-2-4-7(10)8(12)13/h7H,2-5,10H2,1H3,(H2,9,11)(H,12,13)

SMILES

CC(=NCCCCC(C(=O)O)N)N

Synonyms

N-(5-Amino-5-carboxypentyl)-acetamidine;H-Lys(1-iminoethyl)-OH;L-NIL
Method of Synthesis or Extraction
2-Amino-6-(1-aminoethylideneamino)hexanoic acid can be synthesized through various methods, including enzymatic and chemical processes. One commonly used method involves the enzymatic conversion of L-aspartic acid to 2-Amino-6-(1-aminoethylideneamino)hexanoic acid using aspartokinase and homoserine dehydrogenase. Chemical synthesis involves the reaction of L-aspartic acid with acetaldehyde and ammonia. The efficiency and yield of each method vary, with enzymatic methods typically producing higher yields. Environmental and safety considerations must also be taken into account, as some methods may involve the use of hazardous chemicals or generate waste products.
Chemical Structure and Biological Activity
2-Amino-6-(1-aminoethylideneamino)hexanoic acid has a chemical structure similar to that of threonine, with an additional amino group attached to the carbon chain. It has been shown to have biological activity, particularly in its role as a precursor to threonine. 2-Amino-6-(1-aminoethylideneamino)hexanoic acid can also act as a competitive inhibitor of threonine deaminase, an enzyme involved in threonine catabolism.
Biological Effects
2-Amino-6-(1-aminoethylideneamino)hexanoic acid has been studied for its effects on cell function and signal transduction. It has been shown to modulate the activity of certain enzymes and receptors, including the N-methyl-D-aspartate (NMDA) receptor. 2-Amino-6-(1-aminoethylideneamino)hexanoic acid has also been investigated for its potential therapeutic and toxic effects, with some studies suggesting it may have anti-inflammatory and anti-cancer properties.
Future Perspectives and Challenges
Current limitations in the use and study of 2-Amino-6-(1-aminoethylideneamino)hexanoic acid include its potential toxicity and limited understanding of its biological effects. Possible solutions and improvements include further research into its mechanisms of action and development of safer and more efficient synthesis methods. Future trends and prospects in the application of 2-Amino-6-(1-aminoethylideneamino)hexanoic acid in scientific research include its potential use in drug development and environmental management. However, challenges remain in balancing its potential benefits with its potential risks and environmental impact.

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