Fmoc-arg(boc)2-OH - 143824-77-5

Fmoc-arg(boc)2-OH

Catalog Number: EVT-250783
CAS Number: 143824-77-5
Molecular Formula: C31H40N4O8
Molecular Weight: 596,68 g/mole
The product is for non-human research only. Not for therapeutic or veterinary use.
Price:

Product Introduction

Description
Fmoc-arg(boc)2-OH is a chemical compound that belongs to the class of amino acid derivatives. It is widely used in medical, environmental, and industrial research due to its unique properties.
Applications in Various Fields
Fmoc-arg(boc)2-OH has a wide range of applications in medical, environmental, and industrial research. In medical research, Fmoc-arg(boc)2-OH has been used in drug development, clinical trials, and findings. It has been shown to have potential therapeutic effects in the treatment of cancer, inflammation, and autoimmune diseases. However, the potential side effects of Fmoc-arg(boc)2-OH need to be carefully evaluated. In environmental research, Fmoc-arg(boc)2-OH has been used to study its effects on ecosystems, its role in pollution management, and its sustainability and environmental impact. In industrial research, Fmoc-arg(boc)2-OH has been used in manufacturing processes to improve product quality and efficiency. Health and safety considerations need to be taken into account when using Fmoc-arg(boc)2-OH in industrial settings.

Properties

CAS Number

143824-77-5

Product Name

Fmoc-arg(boc)2-OH

IUPAC Name

(2S)-5-[bis[(2-methylpropan-2-yl)oxycarbonylamino]methylideneamino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)pentanoic acid

Molecular Formula

C31H40N4O8

Molecular Weight

596,68 g/mole

InChI

InChI=1S/C31H40N4O8/c1-30(2,3)42-28(39)34-26(35-29(40)43-31(4,5)6)32-17-11-16-24(25(36)37)33-27(38)41-18-23-21-14-9-7-12-19(21)20-13-8-10-15-22(20)23/h7-10,12-15,23-24H,11,16-18H2,1-6H3,(H,33,38)(H,36,37)(H2,32,34,35,39,40)/t24-/m0/s1

InChI Key

QAWFIDADTYJUPT-DEOSSOPVSA-N

SMILES

CC(C)(C)OC(=O)NC(=NCCCC(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13)NC(=O)OC(C)(C)C

Synonyms

N-Fmoc-N',N''-diBoc-L-arginine;FMOC-ARG2-OH;AKOS015841492;AN-31498;FT-0081184;ST24047228;N-alpha-(9-Fluorenylmethyloxycarbonyl)-N',N''-bis-tert-butyloxycarbonyl-L-arginine;N-alpha-(9-Fluorenylmethyloxycarbonyl)-N',N'-bis-tert-butyloxycarbonyl-L-arginine

Canonical SMILES

CC(C)(C)OC(=O)N=C(N)N(CCCC(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13)C(=O)OC(C)(C)C
Method of Synthesis or Extraction
Fmoc-arg(boc)2-OH can be synthesized using various methods, including solid-phase peptide synthesis, solution-phase peptide synthesis, and chemical synthesis. Solid-phase peptide synthesis is the most commonly used method for the synthesis of Fmoc-arg(boc)2-OH. This method involves the stepwise addition of amino acids to a solid support, followed by the removal of the Fmoc protecting group and the boc protecting group. The efficiency and yield of solid-phase peptide synthesis depend on the quality of the starting materials, the reaction conditions, and the purification methods used. The environmental and safety considerations of solid-phase peptide synthesis include the use of hazardous chemicals, the generation of waste, and the potential for contamination.
Chemical Structure and Biological Activity
Fmoc-arg(boc)2-OH has a chemical formula of C32H42N4O8 and a molecular weight of 610.7 g/mol. It is a white to off-white powder that is soluble in organic solvents. Fmoc-arg(boc)2-OH is a potent inhibitor of proteases and has been shown to have anti-inflammatory and anti-tumor properties. The mechanism of action of Fmoc-arg(boc)2-OH involves the inhibition of proteases by binding to their active sites. The biological targets of Fmoc-arg(boc)2-OH include matrix metalloproteinases, cathepsins, and serine proteases. Fmoc-arg(boc)2-OH has been shown to have a high potency against these targets, making it a promising candidate for drug development.
Biological Effects
Fmoc-arg(boc)2-OH has been shown to have a variety of biological effects on cell function and signal transduction. It has been shown to inhibit the migration and invasion of cancer cells, as well as the production of pro-inflammatory cytokines. Fmoc-arg(boc)2-OH has also been shown to induce apoptosis in cancer cells and to enhance the activity of immune cells. However, Fmoc-arg(boc)2-OH may also have potential toxic effects, such as hepatotoxicity and nephrotoxicity, which need to be further investigated.
Future Perspectives and Challenges
The current limitations in the use and study of Fmoc-arg(boc)2-OH include the lack of understanding of its toxicity and the need for further research to evaluate its potential therapeutic effects. Possible solutions and improvements include the development of more efficient and safer synthesis methods, the identification of new biological targets, and the optimization of the chemical structure of Fmoc-arg(boc)2-OH. Future trends and prospects in the application of Fmoc-arg(boc)2-OH in scientific research include the development of new drugs and therapies, the study of its effects on the immune system, and the investigation of its potential use in environmental remediation.
Conclusion:
Fmoc-arg(boc)2-OH is a promising compound with a wide range of applications in medical, environmental, and industrial research. Its unique properties make it a valuable tool for studying biological processes and developing new drugs and therapies. However, the potential toxic effects of Fmoc-arg(boc)2-OH need to be carefully evaluated, and further research is needed to fully understand its biological activity and potential therapeutic effects.

Product FAQ

Q1: How Can I Obtain a Quote for a Product I'm Interested In?
  • To receive a quotation, send us an inquiry about the desired product.
  • The quote will cover pack size options, pricing, and availability details.
  • If applicable, estimated lead times for custom synthesis or sourcing will be provided.
  • Quotations are valid for 30 days, unless specified otherwise.
Q2: What Are the Payment Terms for Ordering Products?
  • New customers generally require full prepayment.
  • NET 30 payment terms can be arranged for customers with established credit.
  • Contact our customer service to set up a credit account for NET 30 terms.
  • We accept purchase orders (POs) from universities, research institutions, and government agencies.
Q3: Which Payment Methods Are Accepted?
  • Preferred methods include bank transfers (ACH/wire) and credit cards.
  • Request a proforma invoice for bank transfer details.
  • For credit card payments, ask sales representatives for a secure payment link.
  • Checks aren't accepted as prepayment, but they can be used for post-payment on NET 30 orders.
Q4: How Do I Place and Confirm an Order?
  • Orders are confirmed upon receiving official order requests.
  • Provide full prepayment or submit purchase orders for credit account customers.
  • Send purchase orders to sales@EVITACHEM.com.
  • A confirmation email with estimated shipping date follows processing.
Q5: What's the Shipping and Delivery Process Like?
  • Our standard shipping partner is FedEx (Standard Overnight, 2Day, FedEx International Priority), unless otherwise agreed.
  • You can use your FedEx account; specify this on the purchase order or inform customer service.
  • Customers are responsible for customs duties and taxes on international shipments.
Q6: How Can I Get Assistance During the Ordering Process?
  • Reach out to our customer service representatives at sales@EVITACHEM.com.
  • For ongoing order updates or questions, continue using the same email.
  • Remember, we're here to help! Feel free to contact us for any queries or further assistance.

Quick Inquiry

 Note: Kindly utilize formal channels such as professional, corporate, academic emails, etc., for inquiries. The use of personal email for inquiries is not advised.