Fmoc-D-3,3-Diphenylalanine - 189937-46-0

Fmoc-D-3,3-Diphenylalanine

Catalog Number: EVT-250930
CAS Number: 189937-46-0
Molecular Formula: C30H25NO4
Molecular Weight: 463,51 g/mole
The product is for non-human research only. Not for therapeutic or veterinary use.
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Product Introduction

Description
Fmoc-D-3,3-Diphenylalanine is a synthetic peptide that has gained significant attention in recent years due to its unique chemical structure and biological activity. It is a derivative of the natural amino acid phenylalanine and is commonly used in medical, environmental, and industrial research. This paper aims to provide a comprehensive review of Fmoc-D-3,3-Diphenylalanine, including its method of synthesis or extraction, chemical structure and biological activity, biological effects, applications, future perspectives, and challenges.
Applications in Various Fields
Fmoc-D-3,3-Diphenylalanine has various applications in medical, environmental, and industrial research. In medical research, it has been used in clinical trials for the treatment of cancer, Alzheimer's disease, and bacterial infections. It has also been used in drug development to improve the efficacy and safety of existing drugs. In environmental research, Fmoc-D-3,3-Diphenylalanine has been used to study its effects on ecosystems and its role in pollution management. In industrial research, it has been used in manufacturing processes to improve product quality and efficiency. However, the use of Fmoc-D-3,3-Diphenylalanine in these applications requires careful consideration of health and safety considerations.

Properties

CAS Number

189937-46-0

Product Name

Fmoc-D-3,3-Diphenylalanine

IUPAC Name

(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3,3-diphenylpropanoic acid

Molecular Formula

C30H25NO4

Molecular Weight

463,51 g/mole

InChI

InChI=1S/C30H25NO4/c32-29(33)28(27(20-11-3-1-4-12-20)21-13-5-2-6-14-21)31-30(34)35-19-26-24-17-9-7-15-22(24)23-16-8-10-18-25(23)26/h1-18,26-28H,19H2,(H,31,34)(H,32,33)/t28-/m1/s1

InChI Key

PENQOTJCVODUQU-MUUNZHRXSA-N

SMILES

C1=CC=C(C=C1)C(C2=CC=CC=C2)C(C(=O)O)NC(=O)OCC3C4=CC=CC=C4C5=CC=CC=C35

Synonyms

189937-46-0;Fmoc-D-3,3-Diphenylalanine;Fmoc-D-Dip-OH;(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3,3-diphenylpropanoicacid;(r)-2-(((9h-fluoren-9-yl)methoxy)carbonylamino)-3,3-diphenylpropanoicacid;AmbotzFAA6280;AC1ODTWG;Fmoc-3,3-diphenyl-D-alaine;SCHEMBL3725850;CTK8E9973;Fmoc-D-Ala(3,3-diphenyl)-OH;MolPort-001-758-558;ZINC2567630;CF-149;AKOS015895701;RTR-008805;VA50268;AJ-41432;AK163631;M470;TL8001549;TR-008805;FT-0643791;ST51052878;N-(9-Fluorenylmethoxycarbonyl)-beta-phenyl-D-phenylalanine

Canonical SMILES

C1=CC=C(C=C1)C(C2=CC=CC=C2)C(C(=O)O)NC(=O)OCC3C4=CC=CC=C4C5=CC=CC=C35

Isomeric SMILES

C1=CC=C(C=C1)C(C2=CC=CC=C2)[C@H](C(=O)O)NC(=O)OCC3C4=CC=CC=C4C5=CC=CC=C35
Method of Synthesis or Extraction
Fmoc-D-3,3-Diphenylalanine can be synthesized using various methods, including solid-phase peptide synthesis (SPPS), solution-phase peptide synthesis (SPPS), and microwave-assisted peptide synthesis. SPPS is the most commonly used method for synthesizing Fmoc-D-3,3-Diphenylalanine due to its efficiency and yield. However, SPPS requires the use of toxic solvents and reagents, which can have adverse environmental and safety considerations. Microwave-assisted peptide synthesis is a relatively new method that has shown promising results in terms of efficiency and yield. However, further research is needed to determine its environmental and safety considerations.
Chemical Structure and Biological Activity
Fmoc-D-3,3-Diphenylalanine has a unique chemical structure that consists of two phenylalanine molecules linked by a peptide bond. It is a hydrophobic molecule that can self-assemble into various nanostructures, including nanotubes, nanospheres, and nanofibers. Fmoc-D-3,3-Diphenylalanine has been shown to exhibit potent antibacterial, antifungal, and antiviral activity. It also has the ability to inhibit the growth of cancer cells and induce apoptosis.
Biological Effects
Fmoc-D-3,3-Diphenylalanine has been shown to have various biological effects on cell function and signal transduction. It can modulate the activity of ion channels, receptors, and enzymes, leading to changes in cellular signaling pathways. Fmoc-D-3,3-Diphenylalanine has also been shown to have potential therapeutic and toxic effects. It has been used in drug development for the treatment of various diseases, including cancer, Alzheimer's disease, and bacterial infections. However, it can also have toxic effects on cells and tissues, leading to adverse side effects.
Future Perspectives and Challenges
Despite the promising results of Fmoc-D-3,3-Diphenylalanine in various applications, there are still limitations in its use and study. One of the main challenges is the lack of understanding of its mechanism of action and biological targets. Further research is needed to determine the optimal conditions for its synthesis and to improve its bioactivity and potency. Future trends and prospects in the application of Fmoc-D-3,3-Diphenylalanine in scientific research include the development of new drug candidates and the study of its potential role in regenerative medicine.
Conclusion:
Fmoc-D-3,3-Diphenylalanine is a synthetic peptide that has gained significant attention in recent years due to its unique chemical structure and biological activity. It has various applications in medical, environmental, and industrial research. However, the use of Fmoc-D-3,3-Diphenylalanine requires careful consideration of health and safety considerations. Further research is needed to determine its optimal conditions for synthesis and to improve its bioactivity and potency.

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