(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-methylhept-6-enoic acid - 288617-77-6

(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-methylhept-6-enoic acid

Catalog Number: EVT-251063
CAS Number: 288617-77-6
Molecular Formula: C23H25NO4
Molecular Weight: 379,45 g/mole
The product is for non-human research only. Not for therapeutic or veterinary use.
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Product Introduction

Description
(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-methylhept-6-enoic acid, also known as FMOC-L-Leucine, is a derivative of the amino acid leucine. It is commonly used in peptide synthesis as a protecting group for the amino group of the leucine residue. FMOC-L-Leucine has also been studied for its potential therapeutic and environmental applications.
Applications in Various Fields
In medical research, (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-methylhept-6-enoic acidne has been used in drug development as a building block for peptide-based therapeutics. Clinical trials have shown promising results for the treatment of various diseases, including cancer and inflammatory disorders. However, potential side effects and toxicity need to be further studied. In environmental research, (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-methylhept-6-enoic acidne has been studied for its effects on ecosystems and its potential role in pollution management. In industrial research, it has been used in manufacturing processes to improve product quality and efficiency, with health and safety considerations being important factors.

Properties

CAS Number

288617-77-6

Product Name

(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-methylhept-6-enoic acid

IUPAC Name

(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-2-methylhept-6-enoic acid

Molecular Formula

C23H25NO4

Molecular Weight

379,45 g/mole

InChI

InChI=1S/C23H25NO4/c1-3-4-9-14-23(2,21(25)26)24-22(27)28-15-20-18-12-7-5-10-16(18)17-11-6-8-13-19(17)20/h3,5-8,10-13,20H,1,4,9,14-15H2,2H3,(H,24,27)(H,25,26)/t23-/m1/s1

InChI Key

MRJFPZWLOJOINV-HSZRJFAPSA-N

SMILES

CC(CCCC=C)(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13

Synonyms

288617-77-6;(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-methylhept-6-enoicacid;(R)-2-{[(9H-fluoren-9-yl)methoxy]carbonylamino}-2-methylhept-6-enoicacid;(2R)-2-[[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]AMINO]-2-METHYL-6-HEPTENOICACID;SCHEMBL1272380;CTK4G2299;Fmoc-D-2-(4'-pentenyl)alanine;MolPort-009-679-981;ZINC36914705;AKOS005063559;CF-1390;(R)-N-Fmoc-2-(4'-pentenyl)alanine;(R)-N-Fmoc-2-(5'-pentenyl)alanine;AJ-93445;AK109522;AM007125;AN-29053;SC-66595;KB-209607;ST2408128;W-2544;(R)-N-Fmoc-2-amino-2-methyl-6-heptenoicacid;I14-7728;(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-2-methyl-hept-6-enoicacid;(2R)-2-(9H-Fluorene-9-ylmethoxycarbonylamino)-2-methyl-6-heptenoicacid

Canonical SMILES

CC(CCCC=C)(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
Method of Synthesis or Extraction
(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-methylhept-6-enoic acidne can be synthesized using various methods, including solid-phase peptide synthesis and solution-phase peptide synthesis. Solid-phase peptide synthesis involves the stepwise addition of protected amino acids to a resin-bound peptide chain, while solution-phase peptide synthesis involves the coupling of protected amino acids in solution. The efficiency and yield of each method depend on the specific conditions used, such as the type of coupling reagent and the reaction time. Environmental and safety considerations include the use of hazardous chemicals and the generation of waste.
Chemical Structure and Biological Activity
(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-methylhept-6-enoic acidne has a chemical structure consisting of a fluorenylmethoxycarbonyl (FMOC) protecting group attached to the amino group of L-leucine. It has been shown to have bioactivity and potency in various biological systems, including inhibition of protein kinase C and modulation of G protein-coupled receptor signaling. Its mechanism of action and biological targets are still being studied.
Biological Effects
(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-methylhept-6-enoic acidne has been shown to have potential therapeutic effects, such as anti-inflammatory and anti-cancer properties. It has also been studied for its potential toxic effects, including cytotoxicity and genotoxicity. Its effects on cell function and signal transduction are still being investigated.
Future Perspectives and Challenges
Current limitations in the use and study of (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-methylhept-6-enoic acidne include its potential toxicity and the need for further research on its biological effects and mechanisms of action. Possible solutions and improvements include the development of safer and more efficient synthesis methods and the identification of new therapeutic targets. Future trends and prospects in the application of (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-methylhept-6-enoic acidne in scientific research include its potential use in personalized medicine and its role in the development of new drug delivery systems.

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