4-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)cyclohexanecarboxylic acid - 188715-40-4

4-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)cyclohexanecarboxylic acid

Catalog Number: EVT-251133
CAS Number: 188715-40-4
Molecular Formula: C23H25NO4
Molecular Weight: 379,46 g/mole
The product is for non-human research only. Not for therapeutic or veterinary use.
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Product Introduction

Description
4-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)cyclohexanecarboxylic acid, also known as FMOC-Lys(Cyhexyl)-OH, is a synthetic amino acid derivative that has gained significant attention in the field of medicinal chemistry due to its potential therapeutic applications. This paper aims to provide an overview of the synthesis, chemical structure, biological activity, and potential applications of FMOC-Lys(Cyhexyl)-OH.
Applications in Various Fields
4-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)cyclohexanecarboxylic acid(Cyhexyl)-OH has several potential applications in medical, environmental, and industrial research. In medical research, it can be used in drug development and clinical trials to evaluate its efficacy and safety. It can also be used to study the mechanisms of cancer cell growth and develop new cancer therapies.
In environmental research, 4-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)cyclohexanecarboxylic acid(Cyhexyl)-OH can be used to study its effects on ecosystems and its role in pollution management. It can also be used to develop sustainable and environmentally friendly manufacturing processes.
In industrial research, 4-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)cyclohexanecarboxylic acid(Cyhexyl)-OH can be used to improve product quality and efficiency. It can also be used to develop new materials and technologies that have health and safety considerations.

Properties

CAS Number

188715-40-4

Product Name

4-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)cyclohexanecarboxylic acid

IUPAC Name

4-[(9H-fluoren-9-ylmethoxycarbonylamino)methyl]cyclohexane-1-carboxylic acid

Molecular Formula

C23H25NO4

Molecular Weight

379,46 g/mole

InChI

InChI=1S/C23H25NO4/c25-22(26)16-11-9-15(10-12-16)13-24-23(27)28-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-8,15-16,21H,9-14H2,(H,24,27)(H,25,26)

InChI Key

MLMIBGARTUSGND-UHFFFAOYSA-N

SMILES

C1CC(CCC1CNC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)C(=O)O

Synonyms

188715-40-4;167690-53-1;4-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)cyclohexanecarboxylicacid;N-Fmoc-tranexamicacid;trans-4-(Fmoc-aminomethyl)cyclohexanecarboxylicacid;TRANS-4-(9-FLUORENYLMETHYLOXYCARBONYLAMINOMETHYL)-CYCLOHEXANOICACID;4-({[(9H-fluoren-9-ylmethoxy)carbonyl]amino}methyl)cyclohexane-1-carboxylicacid;trans-4-({[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}methyl)cyclohexanecarboxylicacid;Trans-4-[[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]methyl]cyclohexanecarboxylicacid;Fmoc-Amc-OH;AmbotzFAA1647;AC1MBSUR;FMOC-TRANEXAMICACID;58446_ALDRICH;SCHEMBL119618;SCHEMBL800277;SCHEMBL14508319;58446_FLUKA;CTK0H4021;CTK0H4176;MLMIBGARTUSGND-WKILWMFISA-N;MolPort-003-725-476;MolPort-027-352-403;ZINC2564732;4-[(9H-fluoren-9-ylmethoxycarbonylamino)methyl]cyclohexane-1-carboxylicAcid

Canonical SMILES

C1CC(CCC1CNC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)C(=O)O
Method of Synthesis or Extraction
4-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)cyclohexanecarboxylic acid(Cyhexyl)-OH can be synthesized using various methods, including solid-phase peptide synthesis (SPPS) and solution-phase peptide synthesis. SPPS is a commonly used method that involves the stepwise addition of amino acids to a growing peptide chain anchored to a solid support. The efficiency and yield of SPPS depend on several factors, including the quality of the starting materials, the reaction conditions, and the purification methods used. Solution-phase peptide synthesis, on the other hand, involves the synthesis of the peptide in solution, followed by purification and isolation of the product. This method is less commonly used due to its lower efficiency and yield.
Environmental and safety considerations are important factors to consider when synthesizing 4-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)cyclohexanecarboxylic acid(Cyhexyl)-OH. The use of hazardous chemicals and solvents, such as dichloromethane and trifluoroacetic acid, can pose a risk to the environment and human health. Therefore, it is essential to follow proper safety protocols and dispose of waste materials appropriately.
Chemical Structure and Biological Activity
4-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)cyclohexanecarboxylic acid(Cyhexyl)-OH is a cyclic amino acid derivative that contains a fluorenylmethoxycarbonyl (FMOC) protecting group, a lysine residue, and a cyclohexylcarboxylic acid moiety. The FMOC group protects the amino group of the lysine residue during peptide synthesis and can be removed using mild acid treatment.
The biological activity of 4-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)cyclohexanecarboxylic acid(Cyhexyl)-OH is attributed to its ability to interact with biological targets, such as enzymes and receptors. The mechanism of action of 4-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)cyclohexanecarboxylic acid(Cyhexyl)-OH is not well understood, but it is believed to modulate cell function and signal transduction pathways.
Biological Effects
4-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)cyclohexanecarboxylic acid(Cyhexyl)-OH has been shown to have potential therapeutic effects, including anti-inflammatory, antimicrobial, and anticancer properties. It has been found to inhibit the growth of cancer cells and induce apoptosis, making it a promising candidate for cancer therapy. However, 4-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)cyclohexanecarboxylic acid(Cyhexyl)-OH can also have toxic effects on cells, depending on the concentration and duration of exposure.
Future Perspectives and Challenges
Despite its potential applications, there are several limitations to the use and study of 4-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)cyclohexanecarboxylic acid(Cyhexyl)-OH. These include its high cost, low solubility, and limited availability. Possible solutions and improvements include the development of more efficient and cost-effective synthesis methods and the optimization of its biological activity and potency.
Future trends and prospects in the application of 4-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)cyclohexanecarboxylic acid(Cyhexyl)-OH in scientific research include its use in personalized medicine and the development of targeted therapies. However, further research is needed to fully understand its biological activity and potential therapeutic effects.

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