c-Met inhibitor 2
Others
C-Met inhibitor 2 is a small molecule inhibitor that targets the c-Met receptor tyrosine kinase. This receptor is involved in various cellular processes, including cell growth, survival, and migration. Overexpression of c-Met has been linked to the development and progression of various cancers, making it an attractive target for cancer therapy.
699.98
699.98
Formulation:
699.98
Source:
Usage:
c-Met inhibitor 2
The product is for non-human research only. Not for therapeutic or veterinary use.
Catalog Number: BT-253102
CAS Number: 1174161-86-4
Molecular Formula: C28H29ClF2N5O10P
Molecular Weight: 699.98
Purity: ≥ 98%
Inventory: In Stock
| Size | SKU | Price | |
|---|---|---|---|
| 10mg | bt-253102-10mg | $1,002.00 |
| CAS Number | 1174161-86-4 |
|---|---|
| Product Name | c-Met inhibitor 2 |
| Molecular Formula | C28H29ClF2N5O10P |
| Molecular Weight | 699.98 |
| InChI | InChI=1S/C24H18ClF2N4O7P.C4H11NO3/c25-21-20(7-8-29-23(21)28)38-19-6-5-15(9-18(19)27)30-24(33)17-11-31(12-37-39(34,35)36)10-16(22(17)32)13-1-3-14(26)4-2-13;5-4(1-6,2-7)3-8/h1-11H,12H2,(H2,28,29)(H,30,33)(H2,34,35,36);6-8H,1-3,5H2 |
| IUPAC Name | [3-[[4-(2-amino-3-chloropyridin-4-yl)oxy-3-fluorophenyl]carbamoyl]-5-(4-fluorophenyl)-4-oxopyridin-1-yl]methyl dihydrogen phosphate;2-amino-2-(hydroxymethyl)propane-1,3-diol |
| Description | C-Met inhibitor 2 is a small molecule inhibitor that targets the c-Met receptor tyrosine kinase. This receptor is involved in various cellular processes, including cell growth, survival, and migration. Overexpression of c-Met has been linked to the development and progression of various cancers, making it an attractive target for cancer therapy. |
| Method of Synthesis or Extraction | C-Met inhibitor 2 can be synthesized using various methods, including chemical synthesis and extraction from natural sources. Chemical synthesis involves the use of organic chemistry techniques to create the molecule. The efficiency and yield of this method depend on the specific reaction conditions and the expertise of the chemist. Environmental and safety considerations must also be taken into account, as some of the reagents used in the synthesis may be hazardous. Extraction from natural sources involves isolating the molecule from plants or other organisms that produce it. This method may be more environmentally friendly, but the yield and purity of the compound may be lower than that obtained through chemical synthesis. |
| Chemical Structure and Biological Activity | The chemical structure of c-Met inhibitor 2 consists of a pyrazolopyrimidine core with various substituents. The molecule binds to the c-Met receptor and inhibits its activity, preventing downstream signaling pathways that promote cell growth and survival. The potency of the inhibitor depends on the specific substituents and their interactions with the receptor. |
| Biological Effects | C-Met inhibitor 2 has been shown to have various effects on cell function and signal transduction. In cancer cells, the inhibitor can induce cell death and inhibit tumor growth. However, the inhibitor may also have potential toxic effects on normal cells, as c-Met is involved in various physiological processes. |
| Applications | In medical research, c-Met inhibitor 2 has been studied for its role in drug development. Clinical trials have shown promising results in the treatment of various cancers, including lung cancer and gastric cancer. However, the inhibitor may also have potential side effects, such as liver toxicity and gastrointestinal disturbances. In environmental research, c-Met inhibitor 2 may have effects on ecosystems and pollution management. The inhibitor may be used to target invasive species or to prevent the spread of pollutants in the environment. However, the potential environmental impact of the inhibitor must also be considered. In industrial research, c-Met inhibitor 2 may be used in manufacturing processes to improve product quality and efficiency. Health and safety considerations must also be taken into account when using the inhibitor in an industrial setting. |
| Future Perspectives and Challenges | Current limitations in the use and study of c-Met inhibitor 2 include its potential toxicity and the need for further research to fully understand its effects on normal cells. Possible solutions and improvements include the development of more specific inhibitors that target only cancer cells and the use of combination therapies to reduce toxicity. Future trends and prospects in the application of c-Met inhibitor 2 in scientific research include the development of personalized medicine approaches that target specific mutations in the c-Met receptor. This may lead to more effective and targeted cancer therapies. However, challenges in the development and approval of new drugs may also arise. Conclusion: c-Met inhibitor 2 is a promising molecule with potential applications in cancer therapy, environmental research, and industrial manufacturing. However, further research is needed to fully understand its effects and potential limitations. The development of more specific inhibitors and personalized medicine approaches may lead to more effective and targeted therapies in the future. |
| SMILES | C1=CC(=CC=C1C2=CN(C=C(C2=O)C(=O)NC3=CC(=C(C=C3)OC4=C(C(=NC=C4)N)Cl)F)COP(=O)(O)O)F.C(C(CO)(CO)N)O |
| Reference | [1]. Robert M. Borzilleri, et al. 4-pyridinone compounds and their use for cancer. WO/2009094417/A1. |
| PubChem Compound | c-Met inhibitor 2 |
| Last Modified | May 30 2023 |