Buy Anpirtoline hydrochloride (BT-253982)

Home > Products > Chemical Compounds > Anpirtoline hydrochloride

Anpirtoline hydrochloride

Catalog Number: BT-253982

CAS Number: 99201-87-3

Molecular Formula: C10H14Cl2N2S

Molecular Weight: 265.2 g/mol

The product is for non-human research only. Not for therapeutic or veterinary use.

INQUIRE NOW

Product Introduction

Description

Anpirtoline hydrochloride is a chemical compound that belongs to the class of pyridine derivatives. It is a potent and selective agonist of the 5-HT1B receptor, which is involved in the regulation of neurotransmitter release and the modulation of pain perception. Anpirtoline hydrochloride has been extensively studied for its potential therapeutic applications in the treatment of various neurological disorders, including migraine, depression, and anxiety.

Properties

CAS Number

99201-87-3

Product Name

Anpirtoline hydrochloride

IUPAC Name

2-chloro-6-piperidin-4-ylsulfanylpyridine;hydrochloride

Molecular Formula

C10H14Cl2N2S

Molecular Weight

265.2 g/mol

InChI

InChI=1S/C10H13ClN2S.ClH/c11-9-2-1-3-10(13-9)14-8-4-6-12-7-5-8;/h1-3,8,12H,4-7H2;1H

InChI Key

GRXDJABVNGUGCW-UHFFFAOYSA-N

SMILES

C1CNCCC1SC2=NC(=CC=C2)Cl.Cl

Synonyms

6-chlor-2-(piperidyl-4-thio)pyridine
6-chloro-2-(piperidyl-4-thiol)pyridine
anpirtoline
anpirtoline hydrochloride
D 16949
D-16949

Canonical SMILES

C1CNCCC1SC2=NC(=CC=C2)Cl.Cl

Method of Synthesis or Extraction

Anpirtoline hydrochloride can be synthesized using various methods, including chemical synthesis and extraction from natural sources. Chemical synthesis involves the reaction of pyridine derivatives with various reagents to produce anpirtoline hydrochloride. The efficiency and yield of this method depend on the purity of the starting materials, the reaction conditions, and the expertise of the chemist. Environmental and safety considerations must also be taken into account, as some of the reagents used in the synthesis process can be hazardous to human health and the environment.
Extraction from natural sources involves the isolation of anpirtoline hydrochloride from plants or other natural sources that contain the compound. This method is often preferred due to its lower environmental impact and potential for higher yields. However, the availability of natural sources of anpirtoline hydrochloride is limited, and the extraction process can be time-consuming and expensive.

Chemical Structure and Biological Activity

The chemical structure of anpirtoline hydrochloride consists of a pyridine ring with a substituted phenyl group and a hydrochloride salt. The compound has a molecular weight of 308.8 g/mol and a melting point of 220-222°C.
Anpirtoline hydrochloride acts as a selective agonist of the 5-HT1B receptor, which is involved in the regulation of neurotransmitter release and the modulation of pain perception. The compound has been shown to have potent bioactivity and potency, with an EC50 value of 0.3 nM for the 5-HT1B receptor.

Biological Effects

Anpirtoline hydrochloride has been shown to have various biological effects on cell function and signal transduction. The compound has been shown to modulate the release of various neurotransmitters, including serotonin, dopamine, and norepinephrine, which are involved in the regulation of mood, pain perception, and other physiological processes.
Anpirtoline hydrochloride has also been studied for its potential therapeutic and toxic effects. The compound has been shown to have potential therapeutic effects in the treatment of various neurological disorders, including migraine, depression, and anxiety. However, the compound has also been shown to have potential toxic effects, including cardiovascular and gastrointestinal side effects.

Applications

Anpirtoline hydrochloride has various applications in medical research, environmental research, and industrial research. In medical research, the compound has been studied for its role in drug development, clinical trials, and findings, and potential benefits and side effects. In environmental research, anpirtoline hydrochloride has been studied for its effects on ecosystems, its role in pollution management, and its sustainability and environmental impact. In industrial research, the compound has been used in manufacturing processes to improve product quality and efficiency, with health and safety considerations taken into account.

Future Perspectives and Challenges

Despite the potential therapeutic and industrial applications of anpirtoline hydrochloride, there are still limitations in its use and study. Possible solutions and improvements include the development of more efficient and sustainable synthesis methods, the identification of new biological targets, and the optimization of dosage and administration methods. Future trends and prospects in the application of anpirtoline hydrochloride in scientific research include the development of new drugs and therapies for various neurological disorders, as well as the continued exploration of its potential industrial applications.

Product FAQ

Q1: How Can I Obtain a Quote for a Product I'm Interested In?

To receive a quotation, send us an inquiry about the desired product.
The quote will cover pack size options, pricing, and availability details.
If applicable, estimated lead times for custom synthesis or sourcing will be provided.
Quotations are valid for 30 days, unless specified otherwise.

Q2: What Are the Payment Terms for Ordering Products?

New customers generally require full prepayment.
NET 30 payment terms can be arranged for customers with established credit.
Contact our customer service to set up a credit account for NET 30 terms.
We accept purchase orders (POs) from universities, research institutions, and government agencies.

Q3: Which Payment Methods Are Accepted?

Preferred methods include bank transfers (ACH/wire) and credit cards.
Request a proforma invoice for bank transfer details.
For credit card payments, ask sales representatives for a secure payment link.
Checks aren't accepted as prepayment, but they can be used for post-payment on NET 30 orders.

Q4: How Do I Place and Confirm an Order?

Orders are confirmed upon receiving official order requests.
Provide full prepayment or submit purchase orders for credit account customers.
Send purchase orders to sales@thebiotek.com.
A confirmation email with estimated shipping date follows processing.

Q5: What's the Shipping and Delivery Process Like?

Our standard shipping partner is FedEx (Standard Overnight, 2Day, FedEx International Priority), unless otherwise agreed.
You can use your FedEx account; specify this on the purchase order or inform customer service.
Customers are responsible for customs duties and taxes on international shipments.

Q6: How Can I Get Assistance During the Ordering Process?

Reach out to our customer service representatives at sales@thebiotek.com.
For ongoing order updates or questions, continue using the same email.
Remember, we're here to help! Feel free to contact us for any queries or further assistance.

Quick Inquiry

Note: Kindly utilize formal channels such as professional, corporate, academic emails, etc., for inquiries. The use of personal email for inquiries is not advised.

Anpirtoline hydrochloride

D-ribose-L-cysteine

Sterubin

Troparil, (+)-

N-Phenyl-d5-N'-[1-(2-phenylethyl)]-4-piperidine

POE (15) tallow amine

5-Cholesten-3beta-25-diol-3-sulfate