Calcium l-aspartate
Catalog Number: BT-254282
CAS Number: 21059-46-1
Molecular Formula: C₄H₅CaNO₄
Molecular Weight: 304.27 g/mol
The product is for non-human research only. Not for therapeutic or veterinary use.
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Product Introduction
Description
Calcium l-aspartate is a chelated form of calcium that is commonly used as a dietary supplement due to its high bioavailability and potential health benefits. It is a combination of calcium and l-aspartic acid, an amino acid that is naturally found in the body. Calcium l-aspartate is known to have a positive effect on bone health, muscle function, and nerve transmission.
Properties
CAS Number
21059-46-1
Product Name
Calcium l-aspartate
IUPAC Name
calcium;(2S)-2-aminobutanedioate
Molecular Formula
C₄H₅CaNO₄
Molecular Weight
304.27 g/mol
InChI
InChI=1S/C4H7NO4.Ca/c5-2(4(8)9)1-3(6)7;/h2H,1,5H2,(H,6,7)(H,8,9);/q;+2/p-2/t2-;/m0./s1
InChI Key
OPSXJNAGCGVGOG-DKWTVANSSA-L
SMILES
C(C(C(=O)[O-])N)C(=O)[O-].[Ca+2]
Synonyms
(+-)-Aspartic Acid
(R,S)-Aspartic Acid
Ammonium Aspartate
Aspartate
Aspartate Magnesium Hydrochloride
Aspartate, Ammonium
Aspartate, Calcium
Aspartate, Dipotassium
Aspartate, Disodium
Aspartate, Magnesium
Aspartate, Monopotassium
Aspartate, Monosodium
Aspartate, Potassium
Aspartate, Sodium
Aspartic Acid
Aspartic Acid, Ammonium Salt
Aspartic Acid, Calcium Salt
Aspartic Acid, Dipotassium Salt
Aspartic Acid, Disodium Salt
Aspartic Acid, Hydrobromide
Aspartic Acid, Hydrochloride
Aspartic Acid, Magnesium (1:1) Salt, Hydrochloride, Trihydrate
Aspartic Acid, Magnesium (2:1) Salt
Aspartic Acid, Magnesium-Potassium (2:1:2) Salt
Aspartic Acid, Monopotassium Salt
Aspartic Acid, Monosodium Salt
Aspartic Acid, Potassium Salt
Aspartic Acid, Sodium Salt
Calcium Aspartate
Dipotassium Aspartate
Disodium Aspartate
L Aspartate
L Aspartic Acid
L-Aspartate
L-Aspartic Acid
Magnesiocard
Magnesium Aspartate
Mg-5-Longoral
Monopotassium Aspartate
Monosodium Aspartate
Potassium Aspartate
Sodium Aspartate
(R,S)-Aspartic Acid
Ammonium Aspartate
Aspartate
Aspartate Magnesium Hydrochloride
Aspartate, Ammonium
Aspartate, Calcium
Aspartate, Dipotassium
Aspartate, Disodium
Aspartate, Magnesium
Aspartate, Monopotassium
Aspartate, Monosodium
Aspartate, Potassium
Aspartate, Sodium
Aspartic Acid
Aspartic Acid, Ammonium Salt
Aspartic Acid, Calcium Salt
Aspartic Acid, Dipotassium Salt
Aspartic Acid, Disodium Salt
Aspartic Acid, Hydrobromide
Aspartic Acid, Hydrochloride
Aspartic Acid, Magnesium (1:1) Salt, Hydrochloride, Trihydrate
Aspartic Acid, Magnesium (2:1) Salt
Aspartic Acid, Magnesium-Potassium (2:1:2) Salt
Aspartic Acid, Monopotassium Salt
Aspartic Acid, Monosodium Salt
Aspartic Acid, Potassium Salt
Aspartic Acid, Sodium Salt
Calcium Aspartate
Dipotassium Aspartate
Disodium Aspartate
L Aspartate
L Aspartic Acid
L-Aspartate
L-Aspartic Acid
Magnesiocard
Magnesium Aspartate
Mg-5-Longoral
Monopotassium Aspartate
Monosodium Aspartate
Potassium Aspartate
Sodium Aspartate
Canonical SMILES
C(C(C(=O)[O-])[NH3+])C(=O)[O-].C(C(C(=O)[O-])[NH3+])C(=O)[O-].O.O.O.[Ca+2]
Isomeric SMILES
C([C@@H](C(=O)[O-])[NH3+])C(=O)[O-].C([C@@H](C(=O)[O-])[NH3+])C(=O)[O-].O.O.O.[Ca+2]
Method of Synthesis or Extraction
Calcium l-aspartate can be synthesized by reacting calcium hydroxide with l-aspartic acid. The reaction takes place in an aqueous solution and is typically carried out at a pH of 9-10. The efficiency and yield of this method depend on the purity of the starting materials and the reaction conditions. Other methods of synthesis include the use of calcium carbonate or calcium chloride as the calcium source. However, these methods are less efficient and may result in lower yields.
Environmental and safety considerations must be taken into account during the synthesis of calcium l-aspartate. The use of strong bases and acids can result in the production of hazardous waste, which must be properly disposed of. Additionally, the use of high temperatures and pressures can result in energy consumption and greenhouse gas emissions.
Environmental and safety considerations must be taken into account during the synthesis of calcium l-aspartate. The use of strong bases and acids can result in the production of hazardous waste, which must be properly disposed of. Additionally, the use of high temperatures and pressures can result in energy consumption and greenhouse gas emissions.
Chemical Structure and Biological Activity
Calcium l-aspartate has a chemical formula of Ca(C4H5NO4)2 and a molecular weight of 324.24 g/mol. It is a white, crystalline powder that is soluble in water. The calcium ion is chelated to the aspartic acid molecule, which enhances its bioavailability and absorption in the body.
The mechanism of action of calcium l-aspartate involves the binding of calcium ions to specific receptors in the body, which triggers a cascade of cellular responses. Calcium is essential for many physiological processes, including muscle contraction, nerve transmission, and bone formation. Calcium l-aspartate has been shown to have a positive effect on bone health, muscle function, and nerve transmission.
The mechanism of action of calcium l-aspartate involves the binding of calcium ions to specific receptors in the body, which triggers a cascade of cellular responses. Calcium is essential for many physiological processes, including muscle contraction, nerve transmission, and bone formation. Calcium l-aspartate has been shown to have a positive effect on bone health, muscle function, and nerve transmission.
Biological Effects
Calcium l-aspartate has been shown to have a variety of biological effects on cell function and signal transduction. It has been shown to enhance the activity of osteoblasts, which are cells responsible for bone formation. Additionally, it has been shown to improve muscle function and reduce muscle fatigue.
Potential therapeutic and toxic effects of calcium l-aspartate must also be considered. While calcium is essential for many physiological processes, excessive intake can lead to hypercalcemia, which can result in kidney stones, gastrointestinal disturbances, and other health problems. Additionally, calcium l-aspartate may interact with certain medications, such as antibiotics and diuretics, which can lead to adverse effects.
Potential therapeutic and toxic effects of calcium l-aspartate must also be considered. While calcium is essential for many physiological processes, excessive intake can lead to hypercalcemia, which can result in kidney stones, gastrointestinal disturbances, and other health problems. Additionally, calcium l-aspartate may interact with certain medications, such as antibiotics and diuretics, which can lead to adverse effects.
Applications
Calcium l-aspartate has a variety of applications in medical, environmental, and industrial research. In medical research, it is commonly used as a dietary supplement to improve bone health, muscle function, and nerve transmission. It has also been studied for its potential role in drug development and clinical trials.
In environmental research, calcium l-aspartate has been studied for its effects on ecosystems and its role in pollution management. It has been shown to have a positive effect on soil quality and plant growth, and may be used to remediate contaminated soils.
In industrial research, calcium l-aspartate is used in manufacturing processes to improve product quality and efficiency. It is also used in the food and beverage industry as a calcium supplement and flavor enhancer.
In environmental research, calcium l-aspartate has been studied for its effects on ecosystems and its role in pollution management. It has been shown to have a positive effect on soil quality and plant growth, and may be used to remediate contaminated soils.
In industrial research, calcium l-aspartate is used in manufacturing processes to improve product quality and efficiency. It is also used in the food and beverage industry as a calcium supplement and flavor enhancer.
Future Perspectives and Challenges
Current limitations in the use and study of calcium l-aspartate include the lack of standardized dosages and the potential for adverse effects. Possible solutions and improvements include the development of standardized dosages and the identification of specific populations that may benefit from calcium l-aspartate supplementation.
Future trends and prospects in the application of calcium l-aspartate in scientific research include the development of new formulations and delivery methods, as well as the identification of new therapeutic targets. Additionally, the use of calcium l-aspartate in combination with other compounds may enhance its bioactivity and potency.
Conclusion:
Calcium l-aspartate is a chelated form of calcium that has a variety of potential health benefits. Its synthesis, biological activity, and applications have been discussed in this paper. While calcium l-aspartate has shown promise in medical, environmental, and industrial research, further studies are needed to fully understand its potential therapeutic and toxic effects.
Future trends and prospects in the application of calcium l-aspartate in scientific research include the development of new formulations and delivery methods, as well as the identification of new therapeutic targets. Additionally, the use of calcium l-aspartate in combination with other compounds may enhance its bioactivity and potency.
Conclusion:
Calcium l-aspartate is a chelated form of calcium that has a variety of potential health benefits. Its synthesis, biological activity, and applications have been discussed in this paper. While calcium l-aspartate has shown promise in medical, environmental, and industrial research, further studies are needed to fully understand its potential therapeutic and toxic effects.
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