Buy 3-(4-(3-Chlorophenyl)piperazin-1-yl)-1,1-diphenylpropan-2-ol dihydrochloride (BT-254317)

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3-(4-(3-Chlorophenyl)piperazin-1-yl)-1,1-diphenylpropan-2-ol dihydrochloride

Catalog Number: BT-254317

CAS Number: 193611-72-2

Molecular Formula: C25H27ClN2O.ClH.ClH

Molecular Weight: 479.9 g/mol

The product is for non-human research only. Not for therapeutic or veterinary use.

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Product Introduction

Description

3-(4-(3-Chlorophenyl)piperazin-1-yl)-1,1-diphenylpropan-2-ol dihydrochloride, also known as Trazodone, is a medication primarily used to treat major depressive disorder. It belongs to the class of drugs known as serotonin receptor antagonists and reuptake inhibitors (SARIs). Trazodone is also used to treat anxiety disorders, insomnia, and chronic pain.

Properties

CAS Number

193611-72-2

Product Name

3-(4-(3-Chlorophenyl)piperazin-1-yl)-1,1-diphenylpropan-2-ol dihydrochloride

IUPAC Name

3-[4-(3-chlorophenyl)piperazin-1-yl]-1,1-diphenylpropan-2-ol;dihydrochloride

Molecular Formula

C25H27ClN2O.ClH.ClH

Molecular Weight

479.9 g/mol

InChI

InChI=1S/C25H27ClN2O.2ClH/c26-22-12-7-13-23(18-22)28-16-14-27(15-17-28)19-24(29)25(20-8-3-1-4-9-20)21-10-5-2-6-11-21;;/h1-13,18,24-25,29H,14-17,19H2;2*1H

InChI Key

WPEXRXMQMPOHIO-UHFFFAOYSA-N

SMILES

C1CN(CCN1CC(C(C2=CC=CC=C2)C3=CC=CC=C3)O)C4=CC(=CC=C4)Cl.Cl.Cl

Synonyms

3-(4-(3-chlorophenyl)piperazin-1-yl)-1,1-diphenyl-2-propanol
BRL 15572
BRL-15572

Canonical SMILES

C1CN(CCN1CC(C(C2=CC=CC=C2)C3=CC=CC=C3)O)C4=CC(=CC=C4)Cl.Cl.Cl

Method of Synthesis or Extraction

3-(4-(3-Chlorophenyl)piperazin-1-yl)-1,1-diphenylpropan-2-ol dihydrochloride can be synthesized using various methods, including the reduction of 3-(4-(3-chlorophenyl)piperazin-1-yl)-1,1-diphenylpropan-2-one with sodium borohydride or lithium aluminum hydride. The efficiency and yield of each method depend on the reaction conditions and the purity of the starting materials. The environmental and safety considerations of the synthesis of 3-(4-(3-Chlorophenyl)piperazin-1-yl)-1,1-diphenylpropan-2-ol dihydrochloride include the use of hazardous chemicals and the generation of waste products. Therefore, it is essential to follow proper safety protocols and dispose of the waste products appropriately.

Chemical Structure and Biological Activity

3-(4-(3-Chlorophenyl)piperazin-1-yl)-1,1-diphenylpropan-2-ol dihydrochloride has a complex chemical structure, consisting of a piperazine ring, a diphenylpropane moiety, and a chlorophenyl group. It acts as an antagonist of the serotonin 5-HT2A receptor and a reuptake inhibitor of serotonin and norepinephrine. 3-(4-(3-Chlorophenyl)piperazin-1-yl)-1,1-diphenylpropan-2-ol dihydrochloride's biological activity is attributed to its ability to increase the levels of serotonin and norepinephrine in the brain, which helps to regulate mood and reduce anxiety.

Biological Effects

3-(4-(3-Chlorophenyl)piperazin-1-yl)-1,1-diphenylpropan-2-ol dihydrochloride has been shown to have various effects on cell function and signal transduction. It has been found to modulate the activity of several neurotransmitter systems, including serotonin, norepinephrine, dopamine, and acetylcholine. 3-(4-(3-Chlorophenyl)piperazin-1-yl)-1,1-diphenylpropan-2-ol dihydrochloride's potential therapeutic effects include its ability to improve mood, reduce anxiety, and alleviate pain. However, it can also have potential toxic effects, such as sedation, dizziness, and nausea.

Applications

3-(4-(3-Chlorophenyl)piperazin-1-yl)-1,1-diphenylpropan-2-ol dihydrochloride has several applications in medical research, including its role in drug development, clinical trials, and findings. It has been found to be effective in treating major depressive disorder, anxiety disorders, and insomnia. 3-(4-(3-Chlorophenyl)piperazin-1-yl)-1,1-diphenylpropan-2-ol dihydrochloride's benefits include its low potential for abuse and addiction, making it a safer alternative to other antidepressants. However, it can also have potential side effects, such as drowsiness, dry mouth, and blurred vision.
In environmental research, 3-(4-(3-Chlorophenyl)piperazin-1-yl)-1,1-diphenylpropan-2-ol dihydrochloride's effects on ecosystems and its role in pollution management and sustainability are still being studied. In industrial research, 3-(4-(3-Chlorophenyl)piperazin-1-yl)-1,1-diphenylpropan-2-ol dihydrochloride is used in manufacturing processes to improve product quality and efficiency. Health and safety considerations are essential when using 3-(4-(3-Chlorophenyl)piperazin-1-yl)-1,1-diphenylpropan-2-ol dihydrochloride in industrial settings.

Future Perspectives and Challenges

The current limitations in the use and study of 3-(4-(3-Chlorophenyl)piperazin-1-yl)-1,1-diphenylpropan-2-ol dihydrochloride include its potential side effects and the need for further research to determine its long-term effects. Possible solutions and improvements include the development of new formulations and dosages that minimize side effects and improve efficacy. Future trends and prospects in the application of 3-(4-(3-Chlorophenyl)piperazin-1-yl)-1,1-diphenylpropan-2-ol dihydrochloride in scientific research include its potential use in the treatment of other psychiatric disorders and chronic pain.
Conclusion:
In conclusion, 3-(4-(3-Chlorophenyl)piperazin-1-yl)-1,1-diphenylpropan-2-ol dihydrochloride is a medication primarily used to treat major depressive disorder, anxiety disorders, and insomnia. Its chemical structure and biological activity make it an effective antidepressant with low potential for abuse and addiction. However, it can also have potential side effects, and its long-term effects are still being studied. Further research is needed to determine its potential use in the treatment of other psychiatric disorders and chronic pain.

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