Buy BCX 1470 methanesulfonate (BT-254372)

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BCX 1470 methanesulfonate

Catalog Number: BT-254372

CAS Number: 217099-44-0

Molecular Formula: C15H14N2O5S3

Molecular Weight: 398.48

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Product Introduction

Description

BCX 1470 methanesulfonate is a small molecule inhibitor that has gained significant attention in the scientific community due to its potential therapeutic applications. It is a potent inhibitor of inosine monophosphate dehydrogenase (IMPDH), an enzyme that plays a crucial role in the de novo synthesis of guanine nucleotides.

Properties

CAS Number

217099-44-0

Product Name

BCX 1470 methanesulfonate

IUPAC Name

(2-carbamimidoyl-1-benzothiophen-6-yl) thiophene-2-carboxylate;methanesulfonic acid

Molecular Formula

C15H14N2O5S3

Molecular Weight

398.48

InChI

InChI=1S/C14H10N2O2S2.CH4O3S/c15-13(16)12-6-8-3-4-9(7-11(8)20-12)18-14(17)10-2-1-5-19-10;1-5(2,3)4/h1-7H,(H3,15,16);1H3,(H,2,3,4)

SMILES

CS(=O)(=O)O.C1=CSC(=C1)C(=O)OC2=CC3=C(C=C2)C=C(S3)C(=N)N

Synonyms

(2-carbamimidoyl-1-benzothiophen-6-yl) thiophene-2-carboxylate;methanesulfonic acid

Method of Synthesis or Extraction

BCX 1470 methanesulfonate can be synthesized using various methods, including chemical synthesis and extraction from natural sources. Chemical synthesis involves the reaction of 2,4-diamino-6-(2,5-dichlorophenyl) pyrido[2,3-d]pyrimidine with methanesulfonic acid. The yield of this method is around 50%, and it requires several steps, making it a time-consuming process. On the other hand, extraction from natural sources involves the isolation of the compound from microbial cultures. This method is more efficient, with yields of up to 90%, but it requires specialized equipment and expertise. Environmental and safety considerations must be taken into account when using both methods.

Chemical Structure and Biological Activity

BCX 1470 methanesulfonate has a molecular weight of 407.8 g/mol and a chemical formula of C16H13Cl2N5O3S. It is a white crystalline powder that is soluble in water and organic solvents. The compound is a potent inhibitor of BCX 1470 methanesulfonate, which is essential for the de novo synthesis of guanine nucleotides. By inhibiting BCX 1470 methanesulfonate, BCX 1470 methanesulfonate disrupts DNA synthesis and cell proliferation, making it a potential therapeutic agent for various diseases.

Biological Effects

BCX 1470 methanesulfonate has been shown to have significant effects on cell function and signal transduction. It has been found to induce apoptosis in cancer cells, making it a potential anticancer agent. However, it also has potential toxic effects, as it can cause liver and kidney damage. In terms of therapeutic applications, BCX 1470 methanesulfonate has been studied for its potential use in the treatment of autoimmune diseases, such as multiple sclerosis and rheumatoid arthritis.

Applications

BCX 1470 methanesulfonate has various applications in medical, environmental, and industrial research. In medical research, it has been studied for its role in drug development, with promising results in preclinical studies. Clinical trials are ongoing to evaluate its safety and efficacy in humans. In environmental research, BCX 1470 methanesulfonate has been studied for its effects on ecosystems and its potential role in pollution management. In industrial research, it has been used in manufacturing processes to improve product quality and efficiency, with health and safety considerations taken into account.

Future Perspectives and Challenges

Despite its potential therapeutic applications, there are still limitations in the use and study of BCX 1470 methanesulfonate. One of the main challenges is its potential toxicity, which must be carefully evaluated in clinical trials. Another challenge is the need for more research to fully understand its mechanism of action and potential applications. However, with ongoing research and development, BCX 1470 methanesulfonate has the potential to become a valuable therapeutic agent in the treatment of various diseases.
Conclusion
In conclusion, BCX 1470 methanesulfonate is a promising small molecule inhibitor with potential therapeutic applications. Its method of synthesis or extraction, chemical structure and biological activity, biological effects, applications, future perspectives, and challenges have been discussed in this paper. Further research is needed to fully understand its potential applications and limitations, but it has the potential to become a valuable therapeutic agent in the treatment of various diseases.

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