Iotalamic acid
Chemical Compounds
Iotalamic acid is a contrast agent used in medical imaging procedures such as X-rays, computed tomography (CT), and magnetic resonance imaging (MRI). It is a water-soluble iodinated compound that enhances the visibility of internal organs and tissues during imaging. Iotalamic acid is also used in environmental and industrial research due to its unique properties.
613.91 g/mol
613.91 g/mol
Formulation:
613.91 g/mol
Source:
Usage:
Iotalamic acid
The product is for non-human research only. Not for therapeutic or veterinary use.
Catalog Number: BT-254399
CAS Number: 2276-90-6
Molecular Formula: C11H9I3N2O4
Molecular Weight: 613.91 g/mol
Purity: ≥ 98%
Inventory: In Stock
| Size | SKU | Price | |
|---|---|---|---|
| 5mg | bt-254399-5mg | $591.85 | |
| 10mg | bt-254399-10mg | $1,104.92 |
| CAS Number | 2276-90-6 |
|---|---|
| Product Name | Iotalamic acid |
| Molecular Formula | C11H9I3N2O4 |
| Molecular Weight | 613.91 g/mol |
| InChI | InChI=1S/C11H9I3N2O4/c1-3(17)16-9-7(13)4(10(18)15-2)6(12)5(8(9)14)11(19)20/h1-2H3,(H,15,18)(H,16,17)(H,19,20) |
| InChI Key | UXIGWFXRQKWHHA-UHFFFAOYSA-N |
| IUPAC Name | 3-acetamido-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid |
| Canonical SMILES | CC(=O)NC1=C(C(=C(C(=C1I)C(=O)O)I)C(=O)NC)I |
| Description | Iotalamic acid is a contrast agent used in medical imaging procedures such as X-rays, computed tomography (CT), and magnetic resonance imaging (MRI). It is a water-soluble iodinated compound that enhances the visibility of internal organs and tissues during imaging. Iotalamic acid is also used in environmental and industrial research due to its unique properties. |
| Method of Synthesis or Extraction | Iotalamic acid is synthesized by reacting 5-amino-2,4,6-triiodoisophthalic acid with iodoacetic acid. The reaction takes place in the presence of a catalyst such as triethylamine. The yield of iotalamic acid is around 70-80%, and the process is relatively efficient. However, the synthesis process requires the use of toxic and hazardous chemicals, which can pose a risk to the environment and human health. Therefore, safety measures must be taken during the synthesis process to minimize the risk of exposure to these chemicals. |
| Chemical Structure and Biological Activity | Iotalamic acid has a molecular formula of C14H8I3NO4 and a molecular weight of 613.93 g/mol. It is a triiodinated derivative of isophthalic acid and contains three iodine atoms that make it an effective contrast agent. Iotalamic acid works by absorbing X-rays and other forms of radiation, which enhances the contrast between the target tissue and surrounding tissues. It is excreted from the body through the kidneys and does not accumulate in the body. |
| Biological Effects | Iotalamic acid has been shown to have potential therapeutic effects on cell function and signal transduction. It has been used in the treatment of liver cancer and other types of cancer. However, it can also have toxic effects on the body, especially if used in high doses or for prolonged periods. Some of the potential side effects of iotalamic acid include allergic reactions, kidney damage, and thyroid dysfunction. |
| Applications | In medical research, iotalamic acid is used in drug development and clinical trials to enhance the visibility of internal organs and tissues during imaging. It is also used in environmental research to study the effects of pollutants on ecosystems and to manage pollution. In industrial research, iotalamic acid is used in manufacturing processes to improve product quality and efficiency. However, health and safety considerations must be taken into account when using iotalamic acid in industrial settings. |
| Future Perspectives and Challenges | Despite its widespread use, iotalamic acid has some limitations in terms of its application and study. For example, it can cause adverse reactions in some patients, and its long-term effects on the body are not well understood. Therefore, more research is needed to fully understand the potential benefits and risks of iotalamic acid. Additionally, new and improved contrast agents are being developed that may offer better performance and fewer side effects. Conclusion: Iotalamic acid is a widely used contrast agent in medical imaging, environmental research, and industrial applications. Its unique properties make it an effective tool for enhancing the visibility of internal organs and tissues during imaging. However, its use must be carefully monitored to minimize the risk of adverse reactions and environmental damage. Further research is needed to fully understand the potential benefits and risks of iotalamic acid and to develop new and improved contrast agents. |
| Other CAS Number | 2276-90-6 |
| Related CAS | 1225-20-3 (mono-hydrochloride salt) |
| SMILES | CC(=O)NC1=C(C(=C(C(=C1I)C(=O)O)I)C(=O)NC)I |
| Synonyms | Acid, Iotalamic Acid, Iothalamic Acid, Methalamic Angio Conray Angio-Conray AngioConray Conray 420 Iodothalamate Iotalamic Acid Iothalamate Iothalamate, Sodium Iothalamic Acid Iothalamic Acid, Calcium (2:1) Salt Iothalamic Acid, Monosilver (1+) Salt Iothalamic Acid, Monosodium Salt Iothalamic Acid, Monosodium Salt, Dimer Lopamidol Methalamic Acid Sodium Iothalamate |
| PubChem Compound | Iotalamic acid |
| Last Modified | May 28 2023 |