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(1R,2S)-2-(3,5-Difluoro-2-phenylmethoxyphenyl)cyclopropan-1-amine;hydrochloride
(1R,2S)-2-(3,5-Difluoro-2-phenylmethoxyphenyl)cyclopropan-1-amine;hydrochloride
Catalog Number: BT-254606
CAS Number: 1239262-36-2
Molecular Formula: C16H15F2NO.HCl
Molecular Weight: 311.75
The product is for non-human research only. Not for therapeutic or veterinary use.
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Product Introduction
Description
(1R,2S)-2-(3,5-Difluoro-2-phenylmethoxyphenyl)cyclopropan-1-amine;hydrochloride, also known as Difluoromethoxyphenyl cyclopropanamine hydrochloride, is a chemical compound that has gained significant attention in the field of medicinal chemistry due to its potential therapeutic effects. This paper aims to provide a comprehensive overview of the synthesis, chemical structure, biological activity, and potential applications of this compound.
Properties
CAS Number
1239262-36-2
Product Name
(1R,2S)-2-(3,5-Difluoro-2-phenylmethoxyphenyl)cyclopropan-1-amine;hydrochloride
IUPAC Name
(1R,2S)-2-(3,5-difluoro-2-phenylmethoxyphenyl)cyclopropan-1-amine;hydrochloride
Molecular Formula
C16H15F2NO.HCl
Molecular Weight
311.75
InChI
InChI=1S/C16H15F2NO.ClH/c17-11-6-13(12-8-15(12)19)16(14(18)7-11)20-9-10-4-2-1-3-5-10;/h1-7,12,15H,8-9,19H2;1H/t12-,15+;/m0./s1
SMILES
C1C(C1N)C2=C(C(=CC(=C2)F)F)OCC3=CC=CC=C3.Cl
Synonyms
(1R,2S)-rel-2-[3,5-Difluoro-2-(phenylmethoxy)phenyl]cycloprpanamine hydrochloride
Method of Synthesis or Extraction
The synthesis of (1R,2S)-2-(3,5-Difluoro-2-phenylmethoxyphenyl)cyclopropan-1-amine;hydrochlorideoxyphenyl cyclopropanamine hydrochloride can be achieved through various methods, including the use of cyclopropanation reactions, Grignard reactions, and reductive amination. The efficiency and yield of each method depend on several factors, such as the availability of starting materials, reaction conditions, and the expertise of the chemist. However, the most commonly used method for the synthesis of this compound is the cyclopropanation reaction, which involves the reaction of an aryl diazo compound with an olefin in the presence of a catalyst.
Environmental and safety considerations are crucial in the synthesis of (1R,2S)-2-(3,5-Difluoro-2-phenylmethoxyphenyl)cyclopropan-1-amine;hydrochlorideoxyphenyl cyclopropanamine hydrochloride. The use of hazardous chemicals and the generation of toxic waste during the synthesis process can have adverse effects on the environment and human health. Therefore, it is essential to follow strict safety protocols and dispose of the waste properly.
Environmental and safety considerations are crucial in the synthesis of (1R,2S)-2-(3,5-Difluoro-2-phenylmethoxyphenyl)cyclopropan-1-amine;hydrochlorideoxyphenyl cyclopropanamine hydrochloride. The use of hazardous chemicals and the generation of toxic waste during the synthesis process can have adverse effects on the environment and human health. Therefore, it is essential to follow strict safety protocols and dispose of the waste properly.
Chemical Structure and Biological Activity
(1R,2S)-2-(3,5-Difluoro-2-phenylmethoxyphenyl)cyclopropan-1-amine;hydrochlorideoxyphenyl cyclopropanamine hydrochloride has a unique chemical structure that consists of a cyclopropane ring attached to a difluoromethoxyphenyl and an amine group. The compound's biological activity is attributed to its ability to interact with specific biological targets, such as monoamine transporters and receptors.
The mechanism of action of (1R,2S)-2-(3,5-Difluoro-2-phenylmethoxyphenyl)cyclopropan-1-amine;hydrochlorideoxyphenyl cyclopropanamine hydrochloride involves the inhibition of the reuptake of monoamine neurotransmitters, such as dopamine, serotonin, and norepinephrine. This leads to an increase in the concentration of these neurotransmitters in the synaptic cleft, resulting in enhanced neurotransmission and mood elevation.
The mechanism of action of (1R,2S)-2-(3,5-Difluoro-2-phenylmethoxyphenyl)cyclopropan-1-amine;hydrochlorideoxyphenyl cyclopropanamine hydrochloride involves the inhibition of the reuptake of monoamine neurotransmitters, such as dopamine, serotonin, and norepinephrine. This leads to an increase in the concentration of these neurotransmitters in the synaptic cleft, resulting in enhanced neurotransmission and mood elevation.
Biological Effects
(1R,2S)-2-(3,5-Difluoro-2-phenylmethoxyphenyl)cyclopropan-1-amine;hydrochlorideoxyphenyl cyclopropanamine hydrochloride has been shown to have potential therapeutic effects in the treatment of various psychiatric disorders, such as depression, anxiety, and attention deficit hyperactivity disorder (ADHD). The compound's effects on cell function and signal transduction are attributed to its ability to modulate the activity of specific neurotransmitter systems in the brain.
However, the compound's potential therapeutic effects are not without potential toxic effects. The use of (1R,2S)-2-(3,5-Difluoro-2-phenylmethoxyphenyl)cyclopropan-1-amine;hydrochlorideoxyphenyl cyclopropanamine hydrochloride can lead to adverse effects, such as cardiovascular complications, seizures, and addiction.
However, the compound's potential therapeutic effects are not without potential toxic effects. The use of (1R,2S)-2-(3,5-Difluoro-2-phenylmethoxyphenyl)cyclopropan-1-amine;hydrochlorideoxyphenyl cyclopropanamine hydrochloride can lead to adverse effects, such as cardiovascular complications, seizures, and addiction.
Applications
(1R,2S)-2-(3,5-Difluoro-2-phenylmethoxyphenyl)cyclopropan-1-amine;hydrochlorideoxyphenyl cyclopropanamine hydrochloride has several potential applications in medical, environmental, and industrial research. In medical research, the compound's role in drug development is of particular interest, with several clinical trials investigating its efficacy and safety in the treatment of psychiatric disorders.
In environmental research, the compound's effects on ecosystems and its role in pollution management are areas of interest. The compound's potential to improve product quality and efficiency in industrial research is also an area of interest, with health and safety considerations being of utmost importance.
In environmental research, the compound's effects on ecosystems and its role in pollution management are areas of interest. The compound's potential to improve product quality and efficiency in industrial research is also an area of interest, with health and safety considerations being of utmost importance.
Future Perspectives and Challenges
Despite the potential therapeutic effects of (1R,2S)-2-(3,5-Difluoro-2-phenylmethoxyphenyl)cyclopropan-1-amine;hydrochlorideoxyphenyl cyclopropanamine hydrochloride, several limitations exist in its use and study. The compound's potential toxic effects and the lack of a clear understanding of its long-term effects on the brain are areas of concern.
Possible solutions and improvements include the development of safer and more effective analogs of the compound and the use of advanced imaging techniques to study its effects on the brain.
Future trends and prospects in the application of (1R,2S)-2-(3,5-Difluoro-2-phenylmethoxyphenyl)cyclopropan-1-amine;hydrochlorideoxyphenyl cyclopropanamine hydrochloride in scientific research include the development of personalized medicine approaches and the use of the compound in combination with other drugs to enhance its therapeutic effects.
Conclusion:
(1R,2S)-2-(3,5-Difluoro-2-phenylmethoxyphenyl)cyclopropan-1-amine;hydrochlorideoxyphenyl cyclopropanamine hydrochloride is a promising compound with potential therapeutic effects in the treatment of psychiatric disorders. However, its potential toxic effects and the lack of a clear understanding of its long-term effects on the brain are areas of concern. Further research is needed to fully understand the compound's potential and limitations in scientific research.
Possible solutions and improvements include the development of safer and more effective analogs of the compound and the use of advanced imaging techniques to study its effects on the brain.
Future trends and prospects in the application of (1R,2S)-2-(3,5-Difluoro-2-phenylmethoxyphenyl)cyclopropan-1-amine;hydrochlorideoxyphenyl cyclopropanamine hydrochloride in scientific research include the development of personalized medicine approaches and the use of the compound in combination with other drugs to enhance its therapeutic effects.
Conclusion:
(1R,2S)-2-(3,5-Difluoro-2-phenylmethoxyphenyl)cyclopropan-1-amine;hydrochlorideoxyphenyl cyclopropanamine hydrochloride is a promising compound with potential therapeutic effects in the treatment of psychiatric disorders. However, its potential toxic effects and the lack of a clear understanding of its long-term effects on the brain are areas of concern. Further research is needed to fully understand the compound's potential and limitations in scientific research.
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