8,11,14-Eicosatriynoic Acid
Catalog Number: BT-254711
CAS Number: 34262-64-1
Molecular Formula: C20H28O2
Molecular Weight: 300.4 g/mol
The product is for non-human research only. Not for therapeutic or veterinary use.
Product Introduction
Description
8,11,14-Eicosatriynoic acid (ETYA) is a polyunsaturated fatty acid that belongs to the omega-3 family. It is a rare fatty acid that is found in small amounts in some plant oils, such as borage and blackcurrant seed oils. ETYA has been the subject of extensive research due to its potential therapeutic and biological effects.
Properties
CAS Number
34262-64-1
Product Name
8,11,14-Eicosatriynoic Acid
IUPAC Name
icosa-8,11,14-triynoic acid
Molecular Formula
C20H28O2
Molecular Weight
300.4 g/mol
InChI
InChI=1S/C20H28O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h2-5,8,11,14-19H2,1H3,(H,21,22)
InChI Key
QLLIWTBTVOPGCM-UHFFFAOYSA-N
SMILES
CCCCCC#CCC#CCC#CCCCCCCC(=O)O
Synonyms
8,11,14-eicosatriynoic acid
Canonical SMILES
CCCCCC#CCC#CCC#CCCCCCCC(=O)O
Method of Synthesis or Extraction
8,11,14-Eicosatriynoic Acid can be synthesized by several methods, including chemical synthesis, enzymatic synthesis, and extraction from natural sources. Chemical synthesis involves the reaction of acetylene with a fatty acid, such as linoleic acid, in the presence of a catalyst. Enzymatic synthesis involves the use of enzymes, such as lipoxygenase, to catalyze the conversion of linoleic acid to 8,11,14-Eicosatriynoic Acid. Extraction from natural sources involves the isolation of 8,11,14-Eicosatriynoic Acid from plant oils, such as borage and blackcurrant seed oils. The efficiency and yield of each method vary, with chemical synthesis being the most efficient and enzymatic synthesis being the least efficient. Environmental and safety considerations should be taken into account when choosing a method of synthesis or extraction, as chemical synthesis can produce hazardous waste and enzymatic synthesis requires the use of enzymes that can be expensive and difficult to obtain.
Chemical Structure and Biological Activity
8,11,14-Eicosatriynoic Acid has a unique chemical structure, with three triple bonds located at positions 8, 11, and 14 of the carbon chain. This structure gives 8,11,14-Eicosatriynoic Acid its biological activity, as it can interact with various biological targets, such as enzymes, receptors, and ion channels. 8,11,14-Eicosatriynoic Acid has been shown to have anti-inflammatory, anti-cancer, and neuroprotective effects. Its mechanism of action involves the modulation of cell signaling pathways, such as the NF-κB and MAPK pathways, and the inhibition of enzymes, such as COX-2 and LOX.
Biological Effects
8,11,14-Eicosatriynoic Acid has been shown to have various biological effects on cell function and signal transduction. It can modulate the expression of genes involved in inflammation, cell proliferation, and apoptosis. 8,11,14-Eicosatriynoic Acid can also affect the activity of ion channels, such as the TRPV1 channel, which is involved in pain sensation. 8,11,14-Eicosatriynoic Acid has potential therapeutic and toxic effects, depending on the dose and duration of exposure. Its therapeutic effects include the prevention and treatment of inflammatory diseases, such as arthritis and asthma, and the inhibition of cancer cell growth. Its toxic effects include the induction of oxidative stress and the inhibition of platelet aggregation.
Applications
8,11,14-Eicosatriynoic Acid has various applications in medical, environmental, and industrial research. In medical research, 8,11,14-Eicosatriynoic Acid has been studied for its role in drug development, clinical trials, and findings, and its benefits and potential side effects. 8,11,14-Eicosatriynoic Acid has been shown to have potential therapeutic effects in the treatment of inflammatory diseases, such as arthritis and asthma, and the inhibition of cancer cell growth. In environmental research, 8,11,14-Eicosatriynoic Acid has been studied for its effects on ecosystems, its role in pollution management, and its sustainability and environmental impact. 8,11,14-Eicosatriynoic Acid has been shown to have potential effects on aquatic organisms, such as fish and algae, and its use in pollution management requires careful consideration of its potential impact on the environment. In industrial research, 8,11,14-Eicosatriynoic Acid has been studied for its use in manufacturing processes, improving product quality and efficiency, and health and safety considerations. 8,11,14-Eicosatriynoic Acid has been shown to have potential applications in the production of biofuels and bioplastics, and its use in industrial processes requires careful consideration of its potential impact on human health and the environment.
Future Perspectives and Challenges
The use and study of 8,11,14-Eicosatriynoic Acid face several limitations, including its low abundance in natural sources, its potential toxicity at high doses, and the lack of standardized methods for its synthesis and analysis. Possible solutions and improvements include the development of more efficient and sustainable methods of synthesis and extraction, the identification of new biological targets and mechanisms of action, and the optimization of dosing and delivery methods. Future trends and prospects in the application of 8,11,14-Eicosatriynoic Acid in scientific research include the development of new drugs and therapies for inflammatory diseases and cancer, the use of 8,11,14-Eicosatriynoic Acid as a biomarker for disease diagnosis and prognosis, and the exploration of its potential applications in environmental and industrial research.
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