Pyrrolidino PAF C-16
Catalog Number: BT-254816
CAS Number: 91021-63-5
Molecular Formula: C28H56NO7P
Molecular Weight: 549.7
The product is for non-human research only. Not for therapeutic or veterinary use.
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Product Introduction
Description
Pyrrolidino PAF C-16 is a phospholipid mediator that plays a crucial role in various physiological and pathological processes. It is a potent inducer of inflammation and is involved in the regulation of vascular permeability, platelet aggregation, and leukocyte activation.
Properties
CAS Number
91021-63-5
Product Name
Pyrrolidino PAF C-16
IUPAC Name
[(2R)-2-acetyloxy-3-hexadecoxypropyl] 2-(1-methylpyrrolidin-1-ium-1-yl)ethyl phosphate
Molecular Formula
C28H56NO7P
Molecular Weight
549.7
InChI
InChI=1S/C28H56NO7P/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-19-23-33-25-28(36-27(2)30)26-35-37(31,32)34-24-22-29(3)20-17-18-21-29/h28H,4-26H2,1-3H3/t28-/m1/s1
InChI Key
QBLLCUIJMABRFJ-MUUNZHRXSA-N
SMILES
CCCCCCCCCCCCCCCCOCC(COP(=O)([O-])OCC[N+]1(CCCC1)C)OC(=O)C
Synonyms
1-O-hexadecyl-2-O-acetyl-sn-glyceryl-3-phosphoryl-N-methyl-pyrrolidinium ethanol
Method of Synthesis or Extraction
Pyrrolidino PAF C-16 can be synthesized using various methods, including chemical synthesis, enzymatic synthesis, and extraction from natural sources. Chemical synthesis involves the use of chemical reactions to produce Pyrrolidino PAF C-16. Enzymatic synthesis involves the use of enzymes to catalyze the synthesis of Pyrrolidino PAF C-16. Extraction from natural sources involves the isolation of Pyrrolidino PAF C-16 from biological tissues or fluids.
The efficiency and yield of each method vary depending on the specific conditions used. Chemical synthesis is the most efficient method, with high yields and purity. Enzymatic synthesis is less efficient but offers the advantage of producing enantiomerically pure Pyrrolidino PAF C-16. Extraction from natural sources is the least efficient method, with low yields and impurities.
Environmental and safety considerations should be taken into account when choosing a method of synthesis or extraction. Chemical synthesis and enzymatic synthesis require the use of hazardous chemicals and enzymes, respectively, which can pose a risk to the environment and human health. Extraction from natural sources can also have an impact on the environment if not done sustainably.
The efficiency and yield of each method vary depending on the specific conditions used. Chemical synthesis is the most efficient method, with high yields and purity. Enzymatic synthesis is less efficient but offers the advantage of producing enantiomerically pure Pyrrolidino PAF C-16. Extraction from natural sources is the least efficient method, with low yields and impurities.
Environmental and safety considerations should be taken into account when choosing a method of synthesis or extraction. Chemical synthesis and enzymatic synthesis require the use of hazardous chemicals and enzymes, respectively, which can pose a risk to the environment and human health. Extraction from natural sources can also have an impact on the environment if not done sustainably.
Chemical Structure and Biological Activity
Pyrrolidino PAF C-16 is a phospholipid mediator that belongs to the family of platelet-activating factors (PAFs). It has a unique chemical structure consisting of a phosphocholine head group, a glycerol backbone, and a long-chain fatty acid with a pyrrolidino group at the sn-2 position.
Pyrrolidino PAF C-16 exerts its biological activity by binding to specific receptors on the surface of target cells. It activates a signaling cascade that leads to the activation of various cellular processes, including inflammation, platelet aggregation, and leukocyte activation. Pyrrolidino PAF C-16 is also involved in the regulation of vascular permeability and smooth muscle contraction.
Pyrrolidino PAF C-16 exerts its biological activity by binding to specific receptors on the surface of target cells. It activates a signaling cascade that leads to the activation of various cellular processes, including inflammation, platelet aggregation, and leukocyte activation. Pyrrolidino PAF C-16 is also involved in the regulation of vascular permeability and smooth muscle contraction.
Biological Effects
Pyrrolidino PAF C-16 has a wide range of biological effects on cell function and signal transduction. It is involved in the regulation of various physiological and pathological processes, including inflammation, immune response, and cardiovascular function.
Pyrrolidino PAF C-16 has potential therapeutic and toxic effects. It has been shown to have anti-inflammatory and anti-tumor properties, making it a potential target for drug development. However, excessive activation of Pyrrolidino PAF C-16 can lead to pathological conditions, such as sepsis, asthma, and cardiovascular diseases.
Pyrrolidino PAF C-16 has potential therapeutic and toxic effects. It has been shown to have anti-inflammatory and anti-tumor properties, making it a potential target for drug development. However, excessive activation of Pyrrolidino PAF C-16 can lead to pathological conditions, such as sepsis, asthma, and cardiovascular diseases.
Applications
Pyrrolidino PAF C-16 has various applications in medical, environmental, and industrial research. In medical research, Pyrrolidino PAF C-16 plays a crucial role in drug development, with several clinical trials investigating its potential therapeutic effects. It is also used as a biomarker for various diseases, including sepsis and asthma.
In environmental research, Pyrrolidino PAF C-16 is used to study its effects on ecosystems and its role in pollution management. It is also used to assess the sustainability and environmental impact of various industrial processes.
In industrial research, Pyrrolidino PAF C-16 is used in manufacturing processes to improve product quality and efficiency. Health and safety considerations should be taken into account when using Pyrrolidino PAF C-16 in industrial applications.
In environmental research, Pyrrolidino PAF C-16 is used to study its effects on ecosystems and its role in pollution management. It is also used to assess the sustainability and environmental impact of various industrial processes.
In industrial research, Pyrrolidino PAF C-16 is used in manufacturing processes to improve product quality and efficiency. Health and safety considerations should be taken into account when using Pyrrolidino PAF C-16 in industrial applications.
Future Perspectives and Challenges
Current limitations in the use and study of Pyrrolidino PAF C-16 include the lack of specific inhibitors and the difficulty in targeting its receptors. Possible solutions and improvements include the development of more specific inhibitors and the use of advanced imaging techniques to study its biological effects.
Future trends and prospects in the application of Pyrrolidino PAF C-16 in scientific research include the development of new drugs targeting its receptors and the use of Pyrrolidino PAF C-16 as a biomarker for various diseases. However, challenges remain in understanding its complex biological effects and its role in various physiological and pathological processes.
Conclusion
Pyrrolidino PAF C-16 is a phospholipid mediator that plays a crucial role in various physiological and pathological processes. Its unique chemical structure and biological activity make it a potential target for drug development and a biomarker for various diseases. However, challenges remain in understanding its complex biological effects and its role in various physiological and pathological processes.
Future trends and prospects in the application of Pyrrolidino PAF C-16 in scientific research include the development of new drugs targeting its receptors and the use of Pyrrolidino PAF C-16 as a biomarker for various diseases. However, challenges remain in understanding its complex biological effects and its role in various physiological and pathological processes.
Conclusion
Pyrrolidino PAF C-16 is a phospholipid mediator that plays a crucial role in various physiological and pathological processes. Its unique chemical structure and biological activity make it a potential target for drug development and a biomarker for various diseases. However, challenges remain in understanding its complex biological effects and its role in various physiological and pathological processes.
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