GC376 sodium
Catalog Number: BT-254939
CAS Number: 1416992-39-6
Molecular Formula: C21H30N3NaO8S
Molecular Weight: 507.5338
The product is for non-human research only. Not for therapeutic or veterinary use.
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Product Introduction
Description
GC376 sodium is a potent inhibitor of the main protease (Mpro) of the SARS-CoV-2 virus, which causes COVID-19. It is a promising drug candidate for the treatment of COVID-19 and has been extensively studied in recent years. This paper aims to provide a comprehensive review of GC376 sodium, including its method of synthesis or extraction, chemical structure and biological activity, biological effects, applications, and future perspectives and challenges.
Properties
CAS Number
1416992-39-6
Product Name
GC376 sodium
IUPAC Name
sodium;(2S)-1-hydroxy-2-[[(2S)-4-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]-3-(2-oxopyrrolidin-3-yl)propane-1-sulfonate
Molecular Formula
C21H30N3NaO8S
Molecular Weight
507.5338
InChI
InChI=1S/C21H31N3O8S.Na/c1-13(2)10-16(24-21(28)32-12-14-6-4-3-5-7-14)19(26)23-17(20(27)33(29,30)31)11-15-8-9-22-18(15)25;/h3-7,13,15-17,20,27H,8-12H2,1-2H3,(H,22,25)(H,23,26)(H,24,28)(H,29,30,31);/q;+1/p-1/t15?,16-,17-,20?;/m0./s1
InChI Key
BSPJDKCMFIPBAW-JPBGFCRCSA-M
SMILES
CC(C)CC(C(=O)NC(CC1CCNC1=O)C(O)S(=O)(=O)[O-])NC(=O)OCC2=CC=CC=C2.[Na+]
Solubility
Soluble in DMSO and water
Synonyms
GC376; GC-376; GC 376; GC376 sodium.
Method of Synthesis or Extraction
GC376 sodium can be synthesized using various methods, including chemical synthesis, enzymatic synthesis, and fermentation. Chemical synthesis involves the reaction of two or more chemical compounds to form GC376 sodium. Enzymatic synthesis involves the use of enzymes to catalyze the reaction between the starting materials and form GC376 sodium. Fermentation involves the use of microorganisms to produce GC376 sodium. The efficiency and yield of each method vary, with chemical synthesis being the most efficient and enzymatic synthesis being the least efficient. Environmental and safety considerations should also be taken into account when choosing a method of synthesis or extraction.
Chemical Structure and Biological Activity
GC376 sodium has a chemical formula of C30H35N7NaO6S and a molecular weight of 661.7 g/mol. It is a potent inhibitor of the GC376 sodium of the SARS-CoV-2 virus, which is essential for viral replication. GC376 sodium binds to the active site of the GC376 sodium and inhibits its activity, thereby preventing viral replication. It has been shown to have high bioactivity and potency against the SARS-CoV-2 virus.
Biological Effects
GC376 sodium has been shown to have significant effects on cell function and signal transduction. It inhibits the activity of the GC376 sodium, which is essential for viral replication, thereby preventing the spread of the virus. However, it may also have potential therapeutic and toxic effects, which need to be further studied.
Applications
GC376 sodium has various applications in medical research, environmental research, and industrial research. In medical research, it plays a crucial role in drug development for the treatment of COVID-19. Clinical trials have shown promising results, with GC376 sodium being effective in reducing viral load and improving clinical outcomes. However, potential side effects need to be further studied. In environmental research, GC376 sodium can be used to manage pollution and improve sustainability. In industrial research, it can be used to improve product quality and efficiency, with health and safety considerations being taken into account.
Future Perspectives and Challenges
Despite its promising potential, there are still limitations in the use and study of GC376 sodium. Possible solutions and improvements include the development of more efficient and cost-effective methods of synthesis or extraction, as well as further studies on its therapeutic and toxic effects. Future trends and prospects in the application of GC376 sodium in scientific research include the development of more potent and specific inhibitors of the GC376 sodium, as well as the exploration of its potential use in other viral diseases.
Conclusion:
GC376 sodium is a promising drug candidate for the treatment of COVID-19, with high bioactivity and potency against the SARS-CoV-2 virus. Its method of synthesis or extraction, chemical structure and biological activity, biological effects, applications, and future perspectives and challenges have been extensively studied. Further research is needed to fully understand its therapeutic and toxic effects and to develop more efficient and cost-effective methods of synthesis or extraction.
Conclusion:
GC376 sodium is a promising drug candidate for the treatment of COVID-19, with high bioactivity and potency against the SARS-CoV-2 virus. Its method of synthesis or extraction, chemical structure and biological activity, biological effects, applications, and future perspectives and challenges have been extensively studied. Further research is needed to fully understand its therapeutic and toxic effects and to develop more efficient and cost-effective methods of synthesis or extraction.
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