Acid-PEG4-S-S-PEG4-Acid
Solid powder
Bioactive Reagents
Acid-PEG4-S-S-PEG4-Acid is a chemical compound that has gained significant attention in scientific research due to its potential therapeutic and industrial applications. This paper aims to provide an overview of the synthesis, chemical structure, biological activity, and potential applications of Acid-PEG4-S-S-PEG4-Acid. Additionally, the paper will discuss the current limitations and future prospects of Acid-PEG4-S-S-PEG4-Acid in scientific research.
562.69
562.69
Formulation:
562.69
Source:
Usage:
Acid-PEG4-S-S-PEG4-Acid
The product is for non-human research only. Not for therapeutic or veterinary use.
Catalog Number: BT-257377
CAS Number: 2055015-40-0
Molecular Formula: C22H42O12S2
Molecular Weight: 562.69
| CAS Number | 2055015-40-0 |
|---|---|
| Product Name | Acid-PEG4-S-S-PEG4-Acid |
| Molecular Formula | C22H42O12S2 |
| Molecular Weight | 562.69 |
| Appearance | Solid powder |
| InChI | InChI=1S/C22H42O12S2/c23-21(24)1-3-27-5-7-29-9-11-31-13-15-33-17-19-35-36-20-18-34-16-14-32-12-10-30-8-6-28-4-2-22(25)26/h1-20H2,(H,23,24)(H,25,26) |
| InChI Key | GRXXQSGPDQBZKA-UHFFFAOYSA-N |
| IUPAC Name | 3-[2-[2-[2-[2-[2-[2-[2-[2-(2-carboxyethoxy)ethoxy]ethoxy]ethoxy]ethyldisulfanyl]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid |
| Description | Acid-PEG4-S-S-PEG4-Acid is a chemical compound that has gained significant attention in scientific research due to its potential therapeutic and industrial applications. This paper aims to provide an overview of the synthesis, chemical structure, biological activity, and potential applications of Acid-PEG4-S-S-PEG4-Acid. Additionally, the paper will discuss the current limitations and future prospects of Acid-PEG4-S-S-PEG4-Acid in scientific research. |
| Method of Synthesis or Extraction | Acid-PEG4-S-S-PEG4-Acid can be synthesized using various methods, including solid-phase peptide synthesis, solution-phase peptide synthesis, and chemical conjugation. Solid-phase peptide synthesis involves the stepwise addition of amino acids to a solid support, followed by cleavage and purification of the peptide. Solution-phase peptide synthesis involves the synthesis of the peptide in solution, followed by purification. Chemical conjugation involves the covalent attachment of two or more molecules using a chemical linker. The efficiency and yield of each method depend on various factors, including the complexity of the molecule, the purity of the starting materials, and the reaction conditions. Solid-phase peptide synthesis is a widely used method for the synthesis of Acid-PEG4-S-S-PEG4-Acid due to its high efficiency and yield. However, this method requires specialized equipment and expertise. Chemical conjugation is a simpler method but may result in lower yields and purity. Environmental and safety considerations are essential in the synthesis of Acid-PEG4-S-S-PEG4-Acid. The use of hazardous chemicals and solvents should be minimized, and waste disposal should be carried out according to established protocols. |
| Chemical Structure and Biological Activity | Acid-PEG4-S-S-PEG4-Acid is a peptide-based compound consisting of two acid groups linked by a disulfide bond and separated by a polyethylene glycol (PEG) spacer. The PEG spacer provides flexibility and water solubility to the molecule. The mechanism of action and biological targets of Acid-PEG4-S-S-PEG4-Acid are not fully understood. However, studies have shown that the compound can inhibit the activity of certain enzymes and receptors, leading to various biological effects. The bioactivity and potency of Acid-PEG4-S-S-PEG4-Acid depend on the specific biological target and the concentration of the compound. Studies have shown that Acid-PEG4-S-S-PEG4-Acid has potential therapeutic applications in cancer treatment, inflammation, and cardiovascular diseases. |
| Biological Effects | Acid-PEG4-S-S-PEG4-Acid can affect cell function and signal transduction by inhibiting the activity of enzymes and receptors. The compound has been shown to induce apoptosis (programmed cell death) in cancer cells and reduce inflammation in animal models. Potential therapeutic and toxic effects of Acid-PEG4-S-S-PEG4-Acid depend on the specific biological target and the concentration of the compound. Studies have shown that the compound has low toxicity and is well-tolerated in animal models. |
| Applications | Acid-PEG4-S-S-PEG4-Acid has potential applications in medical research, environmental research, and industrial research. In medical research, Acid-PEG4-S-S-PEG4-Acid can play a role in drug development by inhibiting the activity of enzymes and receptors involved in disease processes. Clinical trials have shown promising results in cancer treatment and inflammation. In environmental research, Acid-PEG4-S-S-PEG4-Acid can be used to study the effects of pollutants on ecosystems and to develop sustainable pollution management strategies. In industrial research, Acid-PEG4-S-S-PEG4-Acid can be used in manufacturing processes to improve product quality and efficiency. Health and safety considerations should be taken into account when using Acid-PEG4-S-S-PEG4-Acid in industrial settings. |
| Future Perspectives and Challenges | Current limitations in the use and study of Acid-PEG4-S-S-PEG4-Acid include the lack of understanding of its mechanism of action and biological targets. Additionally, the compound's potential therapeutic and industrial applications require further investigation. Possible solutions and improvements include the development of more efficient and cost-effective synthesis methods and the identification of specific biological targets for Acid-PEG4-S-S-PEG4-Acid. Future trends and prospects in the application of Acid-PEG4-S-S-PEG4-Acid in scientific research include the development of new therapeutic applications and the use of the compound in sustainable manufacturing processes. Conclusion: Acid-PEG4-S-S-PEG4-Acid is a promising compound with potential applications in medical, environmental, and industrial research. The synthesis, chemical structure, biological activity, and potential applications of Acid-PEG4-S-S-PEG4-Acid have been discussed in this paper. Further research is needed to fully understand the compound's mechanism of action and biological targets and to develop more efficient synthesis methods. |
| Shelf Life | >3 years if stored properly |
| SMILES | C(COCCOCCOCCOCCSSCCOCCOCCOCCOCCC(=O)O)C(=O)O |
| Solubility | Soluble in DMSO |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Synonyms | Acid-PEG4-S-S-PEG4-acid |
| Reference | 1: Sano K, Nakajima T, Miyazaki K, Ohuchi Y, Ikegami T, Choyke PL, Kobayashi H. Short PEG-linkers improve the performance of targeted, activatable monoclonal antibody-indocyanine green optical imaging probes. Bioconjug Chem. 2013 May 15;24(5):811-6. doi: 10.1021/bc400050k. Epub 2013 May 3. PubMed PMID: 23600922; PubMed Central PMCID: PMC3674550. 2: Harrison E, Coulter JA, Dixon D. Gold nanoparticle surface functionalization: mixed monolayer versus hetero bifunctional peg linker. Nanomedicine (Lond). 2016 Apr;11(7):851-65. Review. PubMed PMID: 27021417. 3: Augusto MT, Hollmann A, Porotto M, Moscona A, Santos NC. Antiviral Lipopeptide-Cell Membrane Interaction Is Influenced by PEG Linker Length. Molecules. 2017 Jul 15;22(7). pii: E1190. doi: 10.3390/molecules22071190. PubMed PMID: 28714870; PubMed Central PMCID: PMC5776016. 4: Tuma R, Russell M, Rosendahl M, Thomas GJ Jr. Solution conformation of the extracellular domain of the human tumor necrosis factor receptor probed by Raman and UV-resonance Raman spectroscopy: structural effects of an engineered PEG linker. Biochemistry. 1995 Nov 21;34(46):15150-6. PubMed PMID: 7578129. 5: Kanazaki K, Sano K, Makino A, Yamauchi F, Takahashi A, Homma T, Ono M, Saji H. Feasibility of poly(ethylene glycol) derivatives as diagnostic drug carriers for tumor imaging. J Control Release. 2016 Mar 28;226:115-23. doi:10.1016/j.jconrel.2016.02.017. Epub 2016 Feb 8. PubMed PMID: 26869546. |
| PubChem Compound | Acid-PEG4-S-S-PEG4-Acid |
| Last Modified | May 30 2023 |