Aspartic acid
Catalog Number: BT-260254
CAS Number: 56-84-8
Molecular Formula: C4H7NO4
Molecular Weight: 133.1 g/mol
The product is for non-human research only. Not for therapeutic or veterinary use.
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Product Introduction
Description
Aspartic acid is a non-essential amino acid that is naturally present in the human body. It is involved in various physiological processes, including protein synthesis, energy production, and neurotransmitter synthesis. Aspartic acid is also found in many food sources, including meat, dairy, and vegetables.
Properties
CAS Number
56-84-8
Product Name
Aspartic acid
IUPAC Name
(2S)-2-aminobutanedioic acid
Molecular Formula
C4H7NO4
Molecular Weight
133.1 g/mol
InChI
InChI=1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m0/s1
InChI Key
CKLJMWTZIZZHCS-REOHCLBHSA-N
SMILES
C(C(C(=O)O)N)C(=O)O
Solubility
5390 mg/L (at 25 °C)
5.36 mg/mL at 25 °C
1 g in 222.2 ml water at 20 °C; 1 g in 149.9 ml water at 30 °C; more sol in salt soln; sol in acids, alkalies
Insoluble in ethanol, ethyl ether, benzene; soluble in dilute HCl, pyridine
In water, 5,360 mg/L at 25 °C
5.39 mg/mL
Solubility in water, g/100ml: 0.45
Slightly soluble in water; Insoluble in ether
Insoluble (in ethanol)
5.36 mg/mL at 25 °C
1 g in 222.2 ml water at 20 °C; 1 g in 149.9 ml water at 30 °C; more sol in salt soln; sol in acids, alkalies
Insoluble in ethanol, ethyl ether, benzene; soluble in dilute HCl, pyridine
In water, 5,360 mg/L at 25 °C
5.39 mg/mL
Solubility in water, g/100ml: 0.45
Slightly soluble in water; Insoluble in ether
Insoluble (in ethanol)
Synonyms
(+-)-Aspartic Acid
(R,S)-Aspartic Acid
Ammonium Aspartate
Aspartate
Aspartate Magnesium Hydrochloride
Aspartate, Ammonium
Aspartate, Calcium
Aspartate, Dipotassium
Aspartate, Disodium
Aspartate, Magnesium
Aspartate, Monopotassium
Aspartate, Monosodium
Aspartate, Potassium
Aspartate, Sodium
Aspartic Acid
Aspartic Acid, Ammonium Salt
Aspartic Acid, Calcium Salt
Aspartic Acid, Dipotassium Salt
Aspartic Acid, Disodium Salt
Aspartic Acid, Hydrobromide
Aspartic Acid, Hydrochloride
Aspartic Acid, Magnesium (1:1) Salt, Hydrochloride, Trihydrate
Aspartic Acid, Magnesium (2:1) Salt
Aspartic Acid, Magnesium-Potassium (2:1:2) Salt
Aspartic Acid, Monopotassium Salt
Aspartic Acid, Monosodium Salt
Aspartic Acid, Potassium Salt
Aspartic Acid, Sodium Salt
Calcium Aspartate
Dipotassium Aspartate
Disodium Aspartate
L Aspartate
L Aspartic Acid
L-Aspartate
L-Aspartic Acid
Magnesiocard
Magnesium Aspartate
Mg-5-Longoral
Monopotassium Aspartate
Monosodium Aspartate
Potassium Aspartate
Sodium Aspartate
(R,S)-Aspartic Acid
Ammonium Aspartate
Aspartate
Aspartate Magnesium Hydrochloride
Aspartate, Ammonium
Aspartate, Calcium
Aspartate, Dipotassium
Aspartate, Disodium
Aspartate, Magnesium
Aspartate, Monopotassium
Aspartate, Monosodium
Aspartate, Potassium
Aspartate, Sodium
Aspartic Acid
Aspartic Acid, Ammonium Salt
Aspartic Acid, Calcium Salt
Aspartic Acid, Dipotassium Salt
Aspartic Acid, Disodium Salt
Aspartic Acid, Hydrobromide
Aspartic Acid, Hydrochloride
Aspartic Acid, Magnesium (1:1) Salt, Hydrochloride, Trihydrate
Aspartic Acid, Magnesium (2:1) Salt
Aspartic Acid, Magnesium-Potassium (2:1:2) Salt
Aspartic Acid, Monopotassium Salt
Aspartic Acid, Monosodium Salt
Aspartic Acid, Potassium Salt
Aspartic Acid, Sodium Salt
Calcium Aspartate
Dipotassium Aspartate
Disodium Aspartate
L Aspartate
L Aspartic Acid
L-Aspartate
L-Aspartic Acid
Magnesiocard
Magnesium Aspartate
Mg-5-Longoral
Monopotassium Aspartate
Monosodium Aspartate
Potassium Aspartate
Sodium Aspartate
Canonical SMILES
C(C(C(=O)O)N)C(=O)O
Isomeric SMILES
C([C@@H](C(=O)O)N)C(=O)O
Method of Synthesis or Extraction
Aspartic acid can be synthesized by several methods, including chemical synthesis, enzymatic synthesis, and microbial fermentation. Chemical synthesis involves the reaction of fumaric acid with ammonia, followed by hydrolysis to produce aspartic acid. Enzymatic synthesis involves the use of aspartate aminotransferase to catalyze the conversion of oxaloacetate to aspartic acid. Microbial fermentation involves the use of microorganisms such as Corynebacterium glutamicum to produce aspartic acid. The efficiency and yield of each method vary, with microbial fermentation being the most efficient and yielding the highest amount of aspartic acid. Environmental and safety considerations are also important, with microbial fermentation being the most environmentally friendly and safe method.
Chemical Structure and Biological Activity
Aspartic acid has a chemical formula of C4H7NO4 and a molecular weight of 133.1 g/mol. It is a dicarboxylic acid with two carboxyl groups and an amino group. Aspartic acid is involved in various biological processes, including protein synthesis, energy production, and neurotransmitter synthesis. It acts as a neurotransmitter in the central nervous system and is involved in the regulation of synaptic transmission. Aspartic acid also plays a role in the regulation of the immune system and the production of hormones.
Biological Effects
Aspartic acid has been shown to have various biological effects on cell function and signal transduction. It has been shown to enhance the activity of the immune system and improve cognitive function. Aspartic acid has also been shown to have potential therapeutic effects, including the treatment of depression, anxiety, and chronic fatigue syndrome. However, aspartic acid can also have toxic effects at high concentrations, including neurotoxicity and excitotoxicity.
Applications
Aspartic acid has various applications in medical research, including its role in drug development, clinical trials, and findings. Aspartic acid has been shown to have potential therapeutic effects in the treatment of depression, anxiety, and chronic fatigue syndrome. Aspartic acid has also been studied for its potential role in cancer treatment and prevention. In environmental research, aspartic acid has been studied for its effects on ecosystems, its role in pollution management, and its sustainability and environmental impact. In industrial research, aspartic acid is used in manufacturing processes to improve product quality and efficiency. Health and safety considerations are also important in industrial research, with aspartic acid being used in a safe and environmentally friendly manner.
Future Perspectives and Challenges
Current limitations in the use and study of aspartic acid include its potential toxic effects at high concentrations and the need for further research to fully understand its biological effects and mechanisms of action. Possible solutions and improvements include the development of new methods for the synthesis and extraction of aspartic acid, as well as the development of new therapeutic applications. Future trends and prospects in the application of aspartic acid in scientific research include its potential use in the treatment of various diseases and its role in the development of new drugs and therapies.
Conclusion:
Aspartic acid is a non-essential amino acid that is involved in various physiological processes. It can be synthesized by several methods, including chemical synthesis, enzymatic synthesis, and microbial fermentation. Aspartic acid has various biological effects on cell function and signal transduction and has potential therapeutic effects in the treatment of various diseases. Aspartic acid has applications in medical research, environmental research, and industrial research. Future perspectives and challenges include the need for further research to fully understand its biological effects and mechanisms of action and the development of new methods for its synthesis and extraction.
Conclusion:
Aspartic acid is a non-essential amino acid that is involved in various physiological processes. It can be synthesized by several methods, including chemical synthesis, enzymatic synthesis, and microbial fermentation. Aspartic acid has various biological effects on cell function and signal transduction and has potential therapeutic effects in the treatment of various diseases. Aspartic acid has applications in medical research, environmental research, and industrial research. Future perspectives and challenges include the need for further research to fully understand its biological effects and mechanisms of action and the development of new methods for its synthesis and extraction.
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