Bifonazole
Solid powder
Others
Bifonazole, also known as mycospor or bay H 4502, belongs to the class of organic compounds known as diphenylmethanes. Diphenylmethanes are compounds containing a diphenylmethane moiety, which consists of a methane wherein two hydrogen atoms are replaced by two phenyl groups. Bifonazole is a drug which is used for the treatment of various topical fungal infections, including athlete's foot (tinea pedis). Bifonazole is considered to be a practically insoluble (in water) and relatively neutral molecule. Bifonazole has been detected in multiple biofluids, such as urine and blood. Within the cell, bifonazole is primarily located in the membrane (predicted from logP).
Bifonazole is an azole antifungal drug.
1-[biphenyl-4-yl(phenyl)methyl]imidazole is a member of the class of imidazoles carrying an alpha-(biphenyl-4-yl)benzyl substituent at position 1. It is a member of imidazoles and a member of biphenyls. 310.4 g/mol
Bifonazole is an azole antifungal drug.
1-[biphenyl-4-yl(phenyl)methyl]imidazole is a member of the class of imidazoles carrying an alpha-(biphenyl-4-yl)benzyl substituent at position 1. It is a member of imidazoles and a member of biphenyls. 310.4 g/mol
Formulation:
310.4 g/mol
Source:
Usage:
Bifonazole
The product is for non-human research only. Not for therapeutic or veterinary use.
Catalog Number: BT-262204
CAS Number: 60628-96-8
Molecular Formula: C22H18N2
Molecular Weight: 310.4 g/mol
| CAS Number | 60628-96-8 |
|---|---|
| Product Name | Bifonazole |
| Molecular Formula | C22H18N2 |
| Molecular Weight | 310.4 g/mol |
| Appearance | Solid powder |
| InChI | InChI=1S/C22H18N2/c1-3-7-18(8-4-1)19-11-13-21(14-12-19)22(24-16-15-23-17-24)20-9-5-2-6-10-20/h1-17,22H |
| InChI Key | OCAPBUJLXMYKEJ-UHFFFAOYSA-N |
| IUPAC Name | 1-[phenyl-(4-phenylphenyl)methyl]imidazole |
| Canonical SMILES | C1=CC=C(C=C1)C2=CC=C(C=C2)C(C3=CC=CC=C3)N4C=CN=C4 |
| Description | Bifonazole, also known as mycospor or bay H 4502, belongs to the class of organic compounds known as diphenylmethanes. Diphenylmethanes are compounds containing a diphenylmethane moiety, which consists of a methane wherein two hydrogen atoms are replaced by two phenyl groups. Bifonazole is a drug which is used for the treatment of various topical fungal infections, including athlete's foot (tinea pedis). Bifonazole is considered to be a practically insoluble (in water) and relatively neutral molecule. Bifonazole has been detected in multiple biofluids, such as urine and blood. Within the cell, bifonazole is primarily located in the membrane (predicted from logP). Bifonazole is an azole antifungal drug. 1-[biphenyl-4-yl(phenyl)methyl]imidazole is a member of the class of imidazoles carrying an alpha-(biphenyl-4-yl)benzyl substituent at position 1. It is a member of imidazoles and a member of biphenyls. |
| Melting Point | 142 |
| Other CAS Number | 60628-96-8 |
| Physical Description | Solid |
| Pictograms | Irritant |
| Shelf Life | >2 years if stored properly |
| SMILES | C1=CC=C(C=C1)C2=CC=C(C=C2)C(C3=CC=CC=C3)N4C=CN=C4 |
| Solubility | Soluble in DMSO, not in water |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Synonyms | 1-((4-biphenylyl)-phenylmethyl)-1H-imidazole Amycor Bay H 4502 Bay H-4502 Bifokey Bifomyk Bifon bifonazole Moldina Mycospo |
| Reference | 1: Piraccini BM, Bruni F, Alessandrini A, Starace M. Evaluation of efficacy and 2: Chen Z, Liu Z, Qian F. Crystallization of bifonazole and acetaminophen within 3: Cheng JS, Chou CT, Liang WZ, Kuo CC, Shieh P, Kuo DH, Jan CR. The mechanism of 4: Tietz HJ, Hay R, Querner S, Delcker A, Kurka P, Merk HF. Efficacy of 4 weeks 5: Lahfa M, Bulai-Livideanu C, Baran R, Ortonne JP, Richert B, Tosti A, Piraccini 6: Abdul Bari MA. Comparison of superficial mycosis treatment using Butenafine 7: Patel D, Patel D, Prajapati J, Patel U, Patel V. Formulation of 8: Wächtler B, Wilson D, Hube B. Candida albicans adhesion to and invasion and 9: El Hage S, Lajoie B, Feuillolay C, Roques C, Baziard G. Synthesis, 10: Billen F, Guieu LV, Bernaerts F, Mercier E, Lavoué R, Tual C, Peeters D, 11: Van Eerdenbrugh B, Fanwick PE, Taylor LS. 12: Linder N, Amarilla M, Hernandez A, Tamiri T, Sirota L, Klinger G, Levy I, 13: Schaller M, Borelli C, Berger U, Walker B, Schmidt S, Weindl G, Jäckel A. 14: Mitsui H, Kanda N, Ohnishi T, Nakai K, Suzuki T, Watanabe S. [Usefulness of 15: Chourbagi C, Andrejak M, Gras V, Peltier M. [Muscle effects due to the 16: Toribio L, del Nozal MJ, Bernal JL, Alonso C, Jiménez JJ. Enantiomeric 17: Watanabe S, Takahashi H, Nishikawa T, Takiuchi I, Higashi N, Nishimoto K, 18: Ferreyra CF, Ortiz CS. Simultaneous determination of bifonazole and tinctures 19: Zhao Y, White MA, Muralidhara BK, Sun L, Halpert JR, Stout CD. Structure of 20: Rupp B, Raub S, Marian C, Höltje HD. Molecular design of two sterol |
| PubChem Compound | Bifonazole |
| Last Modified | Mar 14 2022 |