Dapsone hydroxylamine - 32695-27-5
Dapsone hydroxylamine
Catalog Number: BT-264449
CAS Number: 32695-27-5
Molecular Formula: C12H12N2O3S
Molecular Weight: 264.3 g/mol
The product is for non-human research only. Not for therapeutic or veterinary use.
Product Introduction
Description
Dapsone hydroxylamine is a synthetic compound that has been used in various fields, including medical, environmental, and industrial research. It is a derivative of dapsone, which is an antibiotic used to treat leprosy and other skin conditions. Dapsone hydroxylamine has been found to have potent biological activity and has been studied extensively for its potential therapeutic and toxic effects.
Properties
CAS Number
32695-27-5
Product Name
Dapsone hydroxylamine
IUPAC Name
N-[4-(4-aminophenyl)sulfonylphenyl]hydroxylamine
Molecular Formula
C12H12N2O3S
Molecular Weight
264.3 g/mol
InChI
InChI=1S/C12H12N2O3S/c13-9-1-5-11(6-2-9)18(16,17)12-7-3-10(14-15)4-8-12/h1-8,14-15H,13H2
InChI Key
IYDSJDWESCGRKW-UHFFFAOYSA-N
SMILES
C1=CC(=CC=C1N)S(=O)(=O)C2=CC=C(C=C2)NO
Solubility
Soluble in DMSO
Synonyms
4-amino-4'-hydroxylaminodiphenylsulfone
4-amino-4'-hydroxylaminodiphenylsulfone, T-labeled cpd
4-hydroxylamino-4'-aminophenyl sulfone
dapsone hydroxylamine
DDS-NOH
HADS
N-hydroxydapsone
Canonical SMILES
C1=CC(=CC=C1N)S(=O)(=O)C2=CC=C(C=C2)NO
Method of Synthesis or Extraction
Dapsone hydroxylamine can be synthesized using various methods, including reduction of dapsone with sodium dithionite, sodium borohydride, or zinc dust. The efficiency and yield of each method vary depending on the reaction conditions and the purity of the starting materials. Environmental and safety considerations must also be taken into account when synthesizing dapsone hydroxylamine, as some of the reagents used can be hazardous.
Chemical Structure and Biological Activity
The chemical structure of dapsone hydroxylamine consists of a hydroxylamine group attached to the aromatic ring of dapsone. The mechanism of action of dapsone hydroxylamine is not fully understood, but it is believed to inhibit the activity of enzymes involved in the production of reactive oxygen species, which are involved in various cellular processes. Dapsone hydroxylamine has been found to have potent bioactivity and has been studied for its potential therapeutic effects in various diseases, including cancer, neurodegenerative disorders, and inflammatory conditions.
Biological Effects
Dapsone hydroxylamine has been found to have various effects on cell function and signal transduction. It has been shown to induce apoptosis, inhibit cell proliferation, and modulate the activity of various signaling pathways. Dapsone hydroxylamine has also been studied for its potential therapeutic and toxic effects in various diseases. It has been found to have anti-inflammatory, antioxidant, and neuroprotective effects, but it can also have toxic effects on certain cell types.
Applications
In medical research, dapsone hydroxylamine has been studied for its role in drug development. It has been found to have potential therapeutic effects in various diseases, including cancer, neurodegenerative disorders, and inflammatory conditions. Clinical trials have been conducted to evaluate the safety and efficacy of dapsone hydroxylamine in these diseases. Benefits and potential side effects of dapsone hydroxylamine in these diseases need to be further studied.
In environmental research, dapsone hydroxylamine has been studied for its effects on ecosystems and its role in pollution management. It has been found to have potential applications in the treatment of wastewater and the removal of pollutants from the environment. Sustainability and environmental impact of dapsone hydroxylamine need to be further studied.
In industrial research, dapsone hydroxylamine has been used in various manufacturing processes to improve product quality and efficiency. Health and safety considerations must be taken into account when using dapsone hydroxylamine in industrial applications.
Future Perspectives and Challenges
Current limitations in the use and study of dapsone hydroxylamine include its potential toxicity and the need for further studies to evaluate its safety and efficacy in various diseases. Possible solutions and improvements include the development of more selective and potent derivatives of dapsone hydroxylamine and the use of advanced technologies to study its mechanism of action and biological effects. Future trends and prospects in the application of dapsone hydroxylamine in scientific research include its potential use as a therapeutic agent in various diseases and its role in environmental and industrial applications.
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