Buy Sudan black B (BT-264575)

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Sudan black B

Catalog Number: BT-264575

CAS Number: 4197-25-5

Molecular Formula: C29H24N6

Molecular Weight: 456.5 g/mol

The product is for non-human research only. Not for therapeutic or veterinary use.

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Product Introduction

Description

Sudan black B is a synthetic dye that is commonly used in various scientific research fields, including medical, environmental, and industrial research. It is a lipophilic dye that is soluble in organic solvents and is commonly used to stain lipids, proteins, and nucleic acids. Sudan black B has been extensively studied for its chemical structure, biological activity, and potential applications in various research fields.

Properties

CAS Number

4197-25-5

Product Name

Sudan black B

IUPAC Name

(2,2-dimethyl-1,3-dihydroperimidin-6-yl)-(4-phenyldiazenylnaphthalen-1-yl)diazene

Molecular Formula

C29H24N6

Molecular Weight

456.5 g/mol

InChI

InChI=1S/C29H24N6/c1-29(2)30-26-14-8-13-22-25(17-18-27(31-29)28(22)26)35-34-24-16-15-23(20-11-6-7-12-21(20)24)33-32-19-9-4-3-5-10-19/h3-18,30-31H,1-2H3

InChI Key

YCUVUDODLRLVIC-VPHDGDOJSA-N

SMILES

CC1(NC2=C3C(=C(C=C2)N=NC4=CC=C(C5=CC=CC=C54)N=NC6=CC=CC=C6)C=CC=C3N1)C

Solubility

Soluble in DMSO

Synonyms

CI 26150; CI-26150; CI26150; Sudan Black B

Canonical SMILES

CC1(NC2=C3C(=C(C=C2)N=NC4=CC=C(C5=CC=CC=C54)N=NC6=CC=CC=C6)C=CC=C3N1)C

Method of Synthesis or Extraction

Sudan black B can be synthesized using various methods, including the reaction of p-nitroaniline with benzene in the presence of sulfuric acid and iron filings. Another method involves the reaction of p-nitroaniline with benzene in the presence of sulfuric acid and zinc chloride. The efficiency and yield of each method vary depending on the reaction conditions and the purity of the starting materials. Environmental and safety considerations should also be taken into account when synthesizing Sudan black B, as some of the starting materials and reaction products may be hazardous.

Chemical Structure and Biological Activity

Sudan black B has a complex chemical structure that consists of a benzene ring with multiple nitro and sulfonic acid groups attached to it. It is a lipophilic dye that can easily penetrate cell membranes and stain lipids and proteins. Sudan black B has been shown to inhibit the activity of various enzymes, including lipases and proteases, by binding to their active sites. It also has antimicrobial properties and can inhibit the growth of various bacteria and fungi.

Biological Effects

Sudan black B has been shown to have various biological effects on cell function and signal transduction. It can inhibit the activity of various enzymes involved in lipid metabolism and signal transduction pathways. It has also been shown to induce apoptosis in cancer cells and inhibit the growth of tumors in animal models. However, Sudan black B can also have potential toxic effects on cells and tissues, and its long-term effects on human health are not well understood.

Applications

Sudan black B has various applications in scientific research, including medical, environmental, and industrial research. In medical research, it has been used to study the role of lipids and proteins in various diseases, including cancer, Alzheimer's disease, and cardiovascular disease. It has also been used in clinical trials to evaluate the efficacy of various drugs and therapies. In environmental research, Sudan black B has been used to study the effects of pollutants on ecosystems and to develop strategies for pollution management. In industrial research, it has been used to improve product quality and efficiency and to ensure health and safety in manufacturing processes.

Future Perspectives and Challenges

Despite its potential applications in various research fields, Sudan black B has some limitations in its use and study. Its lipophilic nature and potential toxic effects on cells and tissues require careful consideration when using it in scientific research. Possible solutions and improvements include the development of safer and more efficient methods for synthesizing Sudan black B and the use of alternative dyes and stains that are less toxic and more specific in their biological activity. Future trends and prospects in the application of Sudan black B in scientific research include the development of new drugs and therapies that target lipid metabolism and signal transduction pathways and the use of Sudan black B in the development of new diagnostic tools for various diseases.

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