Flumorph
Catalog Number: BT-268304
CAS Number: 211867-47-9
Molecular Formula: C21H22FNO4
Molecular Weight: 371.4 g/mol
The product is for non-human research only. Not for therapeutic or veterinary use.
Product Introduction
Description
Flumorph is a fungicide that belongs to the phenylamides class of compounds. It is used to control various fungal diseases in crops, including late blight in potatoes and tomatoes. Flumorph has been shown to be effective against a wide range of fungal pathogens, including Phytophthora infestans, which causes late blight in potatoes and tomatoes.
Properties
CAS Number
211867-47-9
Product Name
Flumorph
IUPAC Name
(E)-3-(3,4-dimethoxyphenyl)-3-(4-fluorophenyl)-1-morpholin-4-ylprop-2-en-1-one
Molecular Formula
C21H22FNO4
Molecular Weight
371.4 g/mol
InChI
InChI=1S/C21H22FNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+
InChI Key
BKBSMMUEEAWFRX-NBVRZTHBSA-N
SMILES
COC1=C(C=C(C=C1)C(=CC(=O)N2CCOCC2)C3=CC=C(C=C3)F)OC
Solubility
Soluble in DMSO
Synonyms
Flumorph; SYP-L190; X5977
Canonical SMILES
COC1=C(C=C(C=C1)C(=CC(=O)N2CCOCC2)C3=CC=C(C=C3)F)OC
Isomeric SMILES
COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)F)OC
Method of Synthesis or Extraction
Flumorph can be synthesized using various methods, including the reaction of 2,6-dichloroaniline with 2,3,5,6-tetrafluorobenzonitrile in the presence of a base. The efficiency and yield of the synthesis method depend on the reaction conditions, such as temperature, pressure, and reaction time. The environmental and safety considerations of the synthesis method include the use of hazardous chemicals and the generation of waste products.
Chemical Structure and Biological Activity
The chemical structure of flumorph consists of a phenylamide group and a tetrafluorobenzene ring. The mechanism of action of flumorph involves the inhibition of the mitochondrial respiration of fungal cells. Flumorph targets the succinate dehydrogenase enzyme complex, which is involved in the electron transport chain of the mitochondria. The bioactivity and potency of flumorph depend on the concentration and exposure time. Flumorph has been shown to be effective against various fungal pathogens, including those that are resistant to other fungicides.
Biological Effects
Flumorph has been shown to have various biological effects on cell function and signal transduction. Flumorph inhibits the mitochondrial respiration of fungal cells, leading to the disruption of energy production and cell death. Flumorph has also been shown to affect the expression of genes involved in stress response and cell wall synthesis. The potential therapeutic and toxic effects of flumorph depend on the dose and exposure time. Flumorph has been shown to have low toxicity to mammals and birds.
Applications
Flumorph has various applications in medical research, environmental research, and industrial research. In medical research, flumorph has been used in drug development and clinical trials to control fungal infections. Flumorph has been shown to be effective against various fungal pathogens, including those that are resistant to other fungicides. Flumorph has also been used in environmental research to study its effects on ecosystems and its role in pollution management. In industrial research, flumorph has been used in manufacturing processes to improve product quality and efficiency. Health and safety considerations are important in the use of flumorph in industrial settings.
Future Perspectives and Challenges
The current limitations in the use and study of flumorph include the development of resistance in fungal pathogens and the potential for environmental contamination. Possible solutions and improvements include the development of new formulations and the use of flumorph in combination with other fungicides. Future trends and prospects in the application of flumorph in scientific research include the development of new targets and the use of flumorph in combination with other drugs.
Conclusion
Flumorph is a fungicide that has various applications in medical research, environmental research, and industrial research. The method of synthesis or extraction, chemical structure and biological activity, biological effects, applications, future perspectives, and challenges of flumorph have been discussed in this paper. The use of flumorph in scientific research requires careful consideration of its potential therapeutic and toxic effects, as well as its environmental impact.
Conclusion
Flumorph is a fungicide that has various applications in medical research, environmental research, and industrial research. The method of synthesis or extraction, chemical structure and biological activity, biological effects, applications, future perspectives, and challenges of flumorph have been discussed in this paper. The use of flumorph in scientific research requires careful consideration of its potential therapeutic and toxic effects, as well as its environmental impact.
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