GHK-Cu acetate - 300801-03-0
GHK-Cu acetate
Catalog Number: BT-269175
CAS Number: 300801-03-0
Molecular Formula: C16H26CuN6O6
Molecular Weight: 461.97
The product is for non-human research only. Not for therapeutic or veterinary use.
Product Introduction
Description
GHK-Cu acetate is a copper peptide that has gained significant attention in recent years due to its potential therapeutic and cosmetic applications. It is a naturally occurring tripeptide that is found in human plasma, urine, and saliva. GHK-Cu acetate has been shown to have a wide range of biological activities, including antioxidant, anti-inflammatory, and wound healing properties.
Properties
CAS Number
300801-03-0
Product Name
GHK-Cu acetate
IUPAC Name
copper;acetic acid;(2S)-6-amino-2-[[(2S)-2-(2-aminoacetyl)azanidyl-3-(1H-imidazol-4-yl)propanoyl]amino]hexanoate
Molecular Formula
C16H26CuN6O6
Molecular Weight
461.97
InChI
InChI=1S/C14H24N6O4.C2H4O2.Cu/c15-4-2-1-3-10(14(23)24)20-13(22)11(19-12(21)6-16)5-9-7-17-8-18-9;1-2(3)4;/h7-8,10-11H,1-6,15-16H2,(H4,17,18,19,20,21,22,23,24);1H3,(H,3,4);/q;;+2/p-2/t10-,11-;;/m0../s1
InChI Key
NOIHSRSQDMJJFH-ULEGLUPFSA-L
SMILES
CC(=O)O.C1=C(N=CN1)CC(C(=O)NC(CCCCN)C(=O)[O-])[N-]C(=O)CN.[Cu+2]
Solubility
Soluble in DMSO
Synonyms
GHK-Cu acetate, Gly-His-Lys-Cu(II)
Method of Synthesis or Extraction
GHK-Cu acetate can be synthesized using various methods, including chemical synthesis, enzymatic synthesis, and fermentation. Chemical synthesis involves the reaction of copper acetate with glycyl-L-histidyl-L-lysine to form GHK-Cu acetate. Enzymatic synthesis involves the use of enzymes to catalyze the reaction between copper and GHK. Fermentation involves the use of microorganisms to produce GHK-Cu acetate. Each method has its advantages and disadvantages in terms of efficiency, yield, and environmental and safety considerations.
Chemical Structure and Biological Activity
GHK-Cu acetate has a chemical structure of glycyl-L-histidyl-L-lysine-Cu2+. It has been shown to have a wide range of biological activities, including antioxidant, anti-inflammatory, and wound healing properties. GHK-Cu acetate has been found to stimulate collagen production, which is essential for maintaining healthy skin. It also has been shown to have anti-aging properties by reducing the appearance of fine lines and wrinkles.
Biological Effects
GHK-Cu acetate has been shown to have a significant impact on cell function and signal transduction. It has been found to stimulate the production of growth factors, which are essential for cell growth and repair. GHK-Cu acetate has also been shown to have potential therapeutic and toxic effects. It has been found to have anti-cancer properties by inhibiting the growth of cancer cells. However, it can also be toxic at high concentrations.
Applications
GHK-Cu acetate has a wide range of applications in medical research, environmental research, and industrial research. In medical research, it has been used in drug development and clinical trials. It has been found to have potential therapeutic benefits for various conditions, including skin aging, wound healing, and cancer. However, it also has potential side effects, including skin irritation and allergic reactions. In environmental research, GHK-Cu acetate has been used to study its effects on ecosystems and its role in pollution management. In industrial research, it has been used to improve product quality and efficiency, but health and safety considerations must be taken into account.
Future Perspectives and Challenges
Despite the potential benefits of GHK-Cu acetate, there are still limitations in its use and study. One of the main challenges is the lack of standardization in the production and use of GHK-Cu acetate. There is also a need for more research to determine its safety and efficacy in various applications. However, there are also opportunities for future improvements and trends in the application of GHK-Cu acetate in scientific research, including the development of new formulations and delivery methods.
Conclusion
GHK-Cu acetate is a promising compound with a wide range of potential applications in medical, environmental, and industrial research. Its biological activity and effects on cell function and signal transduction make it a valuable tool for studying various conditions and diseases. However, more research is needed to determine its safety and efficacy in various applications, and standardization in its production and use is necessary. Despite these challenges, GHK-Cu acetate has significant potential for future improvements and trends in scientific research.
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