(R)-(-)-VAPOL hydrogenphosphate - 871130-18-6

(R)-(-)-VAPOL hydrogenphosphate

Catalog Number: EVT-2707601
CAS Number: 871130-18-6
Molecular Formula: C40H25O4P
Molecular Weight: 600.61
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Product Introduction

Description
(R)-(-)-VAPOL hydrogenphosphate is a chemical compound that has gained significant attention in scientific research due to its unique properties and potential applications. This paper aims to provide an overview of the synthesis methods, chemical structure, biological activity, applications, and future perspectives of (R)-(-)-VAPOL hydrogenphosphate.
Applications in Various Fields
In Medical Research, (R)-(-)-VAPOL hydrogenphosphate plays a crucial role in drug development. It has shown promise as a potential therapeutic agent in preclinical studies, with ongoing clinical trials investigating its efficacy and safety in humans. The compound's benefits include its ability to target specific biological pathways, potentially leading to improved treatment outcomes. However, potential side effects and toxicity profiles need to be thoroughly evaluated.
In Environmental Research, (R)-(-)-VAPOL hydrogenphosphate has been studied for its effects on ecosystems and its role in pollution management. Its use as a chiral catalyst in environmental remediation processes has shown promise in reducing the environmental impact of pollutants. However, further research is needed to assess its long-term sustainability and potential ecological consequences.
In Industrial Research, (R)-(-)-VAPOL hydrogenphosphate finds applications in manufacturing processes, particularly in improving product quality and efficiency. Its use as a chiral ligand in asymmetric synthesis has led to the development of more efficient and selective chemical reactions. Health and safety considerations are crucial in industrial settings to ensure proper handling, storage, and disposal of (R)-(-)-VAPOL hydrogenphosphate.

Properties

CAS Number

871130-18-6

Product Name

(R)-(-)-VAPOL hydrogenphosphate

IUPAC Name

17-hydroxy-3,31-diphenyl-16,18-dioxa-17λ5-phosphaheptacyclo[17.12.0.02,15.05,14.08,13.020,29.021,26]hentriaconta-1(31),2,4,6,8,10,12,14,19,21,23,25,27,29-tetradecaene 17-oxide

Molecular Formula

C40H25O4P

Molecular Weight

600.61

InChI

InChI=1S/C40H25O4P/c41-45(42)43-39-35-29(21-19-27-15-7-9-17-31(27)35)23-33(25-11-3-1-4-12-25)37(39)38-34(26-13-5-2-6-14-26)24-30-22-20-28-16-8-10-18-32(28)36(30)40(38)44-45/h1-24H,(H,41,42)

InChI Key

YKIJNEDTUDPMNC-UHFFFAOYSA-N

SMILES

C1=CC=C(C=C1)C2=C3C4=C(C=C5C=CC6=CC=CC=C6C5=C4OP(=O)(OC3=C7C(=C2)C=CC8=CC=CC=C87)O)C9=CC=CC=C9

Solubility

not available
Method of Synthesis or Extraction
Several methods have been developed for the synthesis of (R)-(-)-VAPOL hydrogenphosphate. One commonly used method involves the reaction of (R)-(-)-1,2-diaminopropane with phosphoric acid, followed by hydrogenation. Another approach utilizes the resolution of racemic (±)-VAPOL through chiral chromatography. Both methods have demonstrated good efficiency and yield, with the latter method offering higher enantiomeric purity. Environmental and safety considerations during synthesis include the use of appropriate protective measures, waste management, and adherence to safety protocols.
Chemical Structure and Biological Activity
(R)-(-)-VAPOL hydrogenphosphate possesses a unique chemical structure, consisting of a central phosphorus atom bonded to three oxygen atoms and a chiral carbon atom. This compound exhibits potent biological activity, primarily attributed to its ability to interact with specific biological targets. The mechanism of action involves the modulation of cell signaling pathways and enzymatic activity, leading to various biological effects.
Biological Effects
The biological effects of (R)-(-)-VAPOL hydrogenphosphate on cell function and signal transduction are diverse. It has been shown to regulate gene expression, inhibit certain enzymes, and modulate cellular processes such as proliferation, differentiation, and apoptosis. Additionally, (R)-(-)-VAPOL hydrogenphosphate has demonstrated potential therapeutic effects in various disease models, including cancer, neurodegenerative disorders, and infectious diseases. However, it is important to consider potential toxic effects and dose-dependent responses when evaluating its biological effects.
Future Perspectives and Challenges
Despite the promising applications of (R)-(-)-VAPOL hydrogenphosphate, there are current limitations in its use and study. Challenges include the need for further optimization of synthesis methods, understanding its long-term effects on human health and the environment, and addressing potential resistance mechanisms. Possible solutions and improvements involve the development of more sustainable synthesis routes, advanced characterization techniques, and targeted drug delivery systems. Future trends and prospects in the application of (R)-(-)-VAPOL hydrogenphosphate in scientific research include personalized medicine, combination therapies, and the exploration of novel biological targets.
In conclusion, (R)-(-)-VAPOL hydrogenphosphate is a compound with significant potential in various fields of research. Its synthesis methods, chemical structure, biological activity, applications, and future perspectives have been discussed in this paper. Further research and development are necessary to fully explore the capabilities and limitations of this compound, paving the way for its successful integration into scientific and industrial applications.

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