Indigo carmine
Solid powder
Catalysts and Ligands
Indigo carmine is a synthetic dye that is commonly used in various industries, including medical, environmental, and industrial research. It is a water-soluble compound that is widely used as a pH indicator, and it has been shown to have potential therapeutic and toxic effects. We will also explore the future perspectives and challenges associated with the use of indigo carmine.
466.4 g/mol
466.4 g/mol
Formulation:
466.4 g/mol
Source:
Usage:
Indigo carmine
The product is for non-human research only. Not for therapeutic or veterinary use.
Catalog Number: BT-271012
CAS Number: 860-22-0
Molecular Formula: C16H8N2Na2O8S2
Molecular Weight: 466.4 g/mol
Purity: ≥ 85%
Inventory: In Stock
| Size | SKU | Price | |
|---|---|---|---|
| 5g | bt-271012-5g | $304.77 | |
| 10g | bt-271012-10g | $485.85 | |
| 25g | bt-271012-25g | $309.85 | |
| 50g | bt-271012-50g | $661.08 | |
| 100g | bt-271012-100g | $2,102.31 | |
| 250g | bt-271012-250g | $1,988.62 | |
| 500g | bt-271012-500g | $4,194.31 | |
| 1kg | bt-271012-1kg | $6,901.08 |
| CAS Number | 860-22-0 |
|---|---|
| Product Name | Indigo carmine |
| Molecular Formula | C16H8N2Na2O8S2 |
| Molecular Weight | 466.4 g/mol |
| Appearance | Solid powder |
| Colorform | Purple powder Dark blue powder with coppery luster Blue-red to red-brown powder or dark blue solid |
| InChI | InChI=1S/C16H10N2O8S2.2Na/c19-15-9-5-7(27(21,22)23)1-3-11(9)17-13(15)14-16(20)10-6-8(28(24,25)26)2-4-12(10)18-14;;/h1-6,17,19H,(H,21,22,23)(H,24,25,26);;/q;2*+1/p-2 |
| InChI Key | KHLVKKOJDHCJMG-HLBFIJABSA-L |
| IUPAC Name | disodium;2-(3-hydroxy-5-sulfonato-1H-indol-2-yl)-3-oxoindole-5-sulfonate |
| Canonical SMILES | C1=CC2=C(C=C1S(=O)(=O)[O-])C(=C(N2)C3=NC4=C(C3=O)C=C(C=C4)S(=O)(=O)[O-])O.[Na+].[Na+] |
| Description | Indigo carmine is a synthetic dye that is commonly used in various industries, including medical, environmental, and industrial research. It is a water-soluble compound that is widely used as a pH indicator, and it has been shown to have potential therapeutic and toxic effects. We will also explore the future perspectives and challenges associated with the use of indigo carmine. |
| Method of Synthesis or Extraction | Indigo carmine can be synthesized by several methods, including the oxidation of indigo with sodium hypochlorite, the reaction of indigo with sulfuric acid and nitric acid, and the reaction of indigo with sodium nitrite and hydrochloric acid. The efficiency and yield of each method vary, with the oxidation method being the most efficient and yielding the highest amount of indigo carmine. However, this method also has environmental and safety considerations, as it involves the use of sodium hypochlorite, which is a hazardous chemical. The other methods also have their own limitations, such as low yield and the use of hazardous chemicals. |
| Chemical Structure and Biological Activity | Indigo carmine has a chemical formula of C16H8N2Na2O8S2 and a molecular weight of 466.36 g/mol. It is a sulfonated derivative of indigo, which is a natural dye extracted from the leaves of the indigo plant. Indigo carmine has been shown to have biological activity, particularly in its ability to inhibit the growth of cancer cells. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. It has also been shown to have anti-inflammatory and antioxidant properties. |
| Biological Effects | Indigo carmine has been shown to have various biological effects on cell function and signal transduction. It has been shown to inhibit the growth of cancer cells, as mentioned earlier, and it has also been shown to have anti-inflammatory effects by inhibiting the production of pro-inflammatory cytokines. However, indigo carmine also has potential toxic effects, particularly in high doses. It has been shown to cause liver and kidney damage in animal studies, and it has also been shown to have mutagenic and genotoxic effects. |
| Applications | Indigo carmine has various applications in medical, environmental, and industrial research. In medical research, it is used as a pH indicator in various diagnostic tests, such as endoscopy and urology. It is also being studied for its potential role in drug development, particularly in the treatment of cancer and inflammatory diseases. In environmental research, indigo carmine is used to study the effects of pollutants on ecosystems, and it is also being studied for its potential role in pollution management and sustainability. In industrial research, indigo carmine is used in manufacturing processes to improve product quality and efficiency. However, health and safety considerations must be taken into account when using indigo carmine in industrial settings. |
| Future Perspectives and Challenges | The use of indigo carmine in scientific research is still limited by its potential toxic effects and the lack of understanding of its mechanism of action. Future research should focus on elucidating the biological pathways involved in its anti-cancer and anti-inflammatory effects, as well as its potential toxic effects. Possible solutions and improvements include the development of safer and more efficient methods of synthesis or extraction, as well as the development of new derivatives with improved bioactivity and reduced toxicity. Future trends and prospects in the application of indigo carmine in scientific research include its potential use in personalized medicine and its role in the development of new diagnostic and therapeutic tools. Conclusion: Indigo carmine is a synthetic dye that has various applications in medical, environmental, and industrial research. Its synthesis and extraction methods, chemical structure, biological activity, and potential applications have been discussed in this paper. While indigo carmine has shown potential therapeutic effects, its potential toxic effects must also be taken into account. Future research should focus on elucidating its mechanism of action and developing safer and more efficient methods of synthesis or extraction. |
| Other CAS Number | 860-22-0 16521-38-3 |
| Physical Description | Indigo to dark blue powder. (NTP, 1992) |
| Pictograms | Irritant |
| Shelf Life | >2 years if stored properly |
| SMILES | C1=CC2=C(C=C1S(=O)(=O)[O-])C(=C(N2)C3=NC4=C(C3=O)C=C(C=C4)S(=O)(=O)[O-])O.[Na+].[Na+] |
| Solubility | 10 to 50 mg/mL at 70.7° F (NTP, 1992) Slightly soluble in alcohol; practically insoluble in most other organic solvents Insoluble in benzene, chloroform 9 mg/mL in ethyleneglycol monomethyl ether; 3 mg/mL in ethanol Soluble in water, ethanol; insoluble in organic solvents In water, 3 mg/mL One gram dissolves in about 100 mL water at 25 °C |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Synonyms | (delta-2,2'-biindole)-3,3'-dione 2-(1,3-Dihydro-3-oxo-5-sulpho-2H-indol-2-ylidene)-3- oxoindoline-5-sulphonic acid Carmine, Indigo D and C Blue NO. 6 FD and C Blue No. 2 indigo Indigo Blue Indigo Blue, Soluble Indigo Carmine Indigo Disulfonate indigotin Indigotindisulfonate Indigotindisulfonate Sodium Indigotindisulfonic Acid Soluble Indigo Blue |
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| PubChem Compound | Indigo carmine |
| Last Modified | May 30 2023 |