Isophthalic acid
Catalog Number: BT-272346
CAS Number: 121-91-5
Molecular Formula: C8H6O4
C6H4(COOH)2
C8H6O4
C6H4(COOH)2
C8H6O4
Molecular Weight: 166.13 g/mol
The product is for non-human research only. Not for therapeutic or veterinary use.
Price:
Product Introduction
Description
Isophthalic acid (IPA) is a white crystalline solid with the chemical formula C8H6O4. It is an isomer of phthalic acid and is widely used in the production of polymers, resins, and coatings. IPA is also used in medical and environmental research due to its biological activity and potential therapeutic effects.
Properties
CAS Number
121-91-5
Product Name
Isophthalic acid
IUPAC Name
benzene-1,3-dicarboxylic acid
Molecular Formula
C8H6O4
C6H4(COOH)2
C8H6O4
C6H4(COOH)2
C8H6O4
Molecular Weight
166.13 g/mol
InChI
InChI=1S/C8H6O4/c9-7(10)5-2-1-3-6(4-5)8(11)12/h1-4H,(H,9,10)(H,11,12)
InChI Key
QQVIHTHCMHWDBS-UHFFFAOYSA-N
SMILES
C1=CC(=CC(=C1)C(=O)O)C(=O)O
Solubility
6.02e-04 M
Soluble in 8000 parts cold water, 460 parts boiling water; freely soluble in alcohol; practically insoluble in petroleum ether
In methanol: 4.0 g/100 g at 25 °C; in propanol: 1.7 g/100 g at 25 °C, 2.7 g/100 g at 50 °C; in glacial acetic acid: 0.23 g/100 g at 25 °C
Insoluble in benzene, ligroin and ether
Water solubility: 120 mg/L at 25 °C, 350 mg/L at 50 °C, 3200 mg/L at 100 °C
In water, 5400 mg/L at 14 °C (pH adjusted water for complete dissociation)
Solubility in water: none in cold water, poor in boiling wate
Soluble in 8000 parts cold water, 460 parts boiling water; freely soluble in alcohol; practically insoluble in petroleum ether
In methanol: 4.0 g/100 g at 25 °C; in propanol: 1.7 g/100 g at 25 °C, 2.7 g/100 g at 50 °C; in glacial acetic acid: 0.23 g/100 g at 25 °C
Insoluble in benzene, ligroin and ether
Water solubility: 120 mg/L at 25 °C, 350 mg/L at 50 °C, 3200 mg/L at 100 °C
In water, 5400 mg/L at 14 °C (pH adjusted water for complete dissociation)
Solubility in water: none in cold water, poor in boiling wate
Synonyms
isophthalate
isophthalate, calcium (1:1)salt
isophthalate, copper (+2) salt
isophthalate, copper (+2) salt (1:1)
isophthalate, disodium salt
isophthalate, iron (+2) salt
isophthalate, iron (+2) salt (1:1)
isophthalic acid
isophthalate, calcium (1:1)salt
isophthalate, copper (+2) salt
isophthalate, copper (+2) salt (1:1)
isophthalate, disodium salt
isophthalate, iron (+2) salt
isophthalate, iron (+2) salt (1:1)
isophthalic acid
Canonical SMILES
[H+].[H+].C1=CC(=CC(=C1)C(=O)[O-])C(=O)[O-]
Method of Synthesis or Extraction
Isophthalic acid can be synthesized by several methods, including the oxidation of meta-xylene, the reaction of benzene with carbon monoxide and water, and the reaction of terephthalic acid with methanol. The efficiency and yield of each method vary depending on the reaction conditions and the purity of the starting materials. The oxidation of meta-xylene is the most commonly used method, with a yield of up to 90%. However, this method requires high temperatures and pressures and produces a large amount of waste. The reaction of benzene with carbon monoxide and water is a more environmentally friendly method, but it has a lower yield of around 60%. The reaction of terephthalic acid with methanol is a simple and efficient method, but it requires a high temperature and produces a large amount of methanol as a byproduct.
Chemical Structure and Biological Activity
Isophthalic acid has a benzene ring with two carboxylic acid groups attached to it. It is a dicarboxylic acid and is soluble in water and organic solvents. Isophthalic acid has been shown to have biological activity, including anti-inflammatory, antioxidant, and anticancer effects. It acts by inhibiting the activity of enzymes involved in inflammation and oxidative stress and by inducing apoptosis in cancer cells. Isophthalic acid has also been shown to have antibacterial and antifungal activity.
Biological Effects
Isophthalic acid has been shown to have a variety of biological effects on cell function and signal transduction. It has been shown to inhibit the production of pro-inflammatory cytokines and chemokines, which are involved in the immune response. Isophthalic acid has also been shown to inhibit the activity of NF-κB, a transcription factor that regulates the expression of genes involved in inflammation and cell survival. In addition, Isophthalic acid has been shown to induce apoptosis in cancer cells by activating the caspase pathway and inhibiting the PI3K/Akt pathway. However, Isophthalic acid can also have potential toxic effects, including liver and kidney damage, if consumed in large amounts.
Applications
Isophthalic acid has a wide range of applications in medical, environmental, and industrial research. In medical research, Isophthalic acid is used in drug development and clinical trials. It has been shown to have potential therapeutic effects in the treatment of cancer, inflammation, and oxidative stress. However, further research is needed to determine its safety and efficacy in humans. In environmental research, Isophthalic acid is used to study its effects on ecosystems and its role in pollution management. It has been shown to have a low toxicity to aquatic organisms and can be used as a biodegradable alternative to other chemicals. In industrial research, Isophthalic acid is used in the manufacturing of polymers, resins, and coatings. It can improve product quality and efficiency and has health and safety considerations due to its potential toxicity.
Future Perspectives and Challenges
The use of Isophthalic acid in scientific research is limited by its potential toxicity and the need for further research to determine its safety and efficacy. Possible solutions and improvements include the development of new synthesis methods that are more environmentally friendly and the use of Isophthalic acid in combination with other compounds to enhance its biological activity. Future trends and prospects in the application of Isophthalic acid in scientific research include the development of new drugs and therapies that target inflammation, oxidative stress, and cancer. However, the challenges of developing safe and effective treatments remain, and further research is needed to overcome these challenges.
Conclusion:
Isophthalic acid is a versatile compound with a wide range of applications in scientific research. Its synthesis methods, chemical structure, and biological activity have been studied extensively, and it has been shown to have potential therapeutic effects in the treatment of cancer, inflammation, and oxidative stress. However, its potential toxicity and the need for further research to determine its safety and efficacy remain challenges in its use. The future prospects of Isophthalic acid in scientific research are promising, and further research is needed to develop safe and effective treatments.
Conclusion:
Isophthalic acid is a versatile compound with a wide range of applications in scientific research. Its synthesis methods, chemical structure, and biological activity have been studied extensively, and it has been shown to have potential therapeutic effects in the treatment of cancer, inflammation, and oxidative stress. However, its potential toxicity and the need for further research to determine its safety and efficacy remain challenges in its use. The future prospects of Isophthalic acid in scientific research are promising, and further research is needed to develop safe and effective treatments.
Product FAQ
Q1: How Can I Obtain a Quote for a Product I'm Interested In?
- To receive a quotation, send us an inquiry about the desired product.
- The quote will cover pack size options, pricing, and availability details.
- If applicable, estimated lead times for custom synthesis or sourcing will be provided.
- Quotations are valid for 30 days, unless specified otherwise.
Q2: What Are the Payment Terms for Ordering Products?
- New customers generally require full prepayment.
- NET 30 payment terms can be arranged for customers with established credit.
- Contact our customer service to set up a credit account for NET 30 terms.
- We accept purchase orders (POs) from universities, research institutions, and government agencies.
Q3: Which Payment Methods Are Accepted?
- Preferred methods include bank transfers (ACH/wire) and credit cards.
- Request a proforma invoice for bank transfer details.
- For credit card payments, ask sales representatives for a secure payment link.
- Checks aren't accepted as prepayment, but they can be used for post-payment on NET 30 orders.
Q4: How Do I Place and Confirm an Order?
- Orders are confirmed upon receiving official order requests.
- Provide full prepayment or submit purchase orders for credit account customers.
- Send purchase orders to sales@thebiotek.com.
- A confirmation email with estimated shipping date follows processing.
Q5: What's the Shipping and Delivery Process Like?
- Our standard shipping partner is FedEx (Standard Overnight, 2Day, FedEx International Priority), unless otherwise agreed.
- You can use your FedEx account; specify this on the purchase order or inform customer service.
- Customers are responsible for customs duties and taxes on international shipments.
Q6: How Can I Get Assistance During the Ordering Process?
- Reach out to our customer service representatives at sales@thebiotek.com.
- For ongoing order updates or questions, continue using the same email.
- Remember, we're here to help! Feel free to contact us for any queries or further assistance.
Quick Inquiry
Note: Kindly utilize formal channels such as professional, corporate, academic emails, etc., for inquiries. The use of personal email for inquiries is not advised.
Category
Hot Products
2-Oxo-3-hydroxy-lysergide
CAS No.: 111295-09-1
Sterubin
CAS No.: 51857-11-5
Uricytin
CAS No.: 40919-33-3
Gadolinium (III) isopropoxide
CAS No.: 14532-05-9
5-Chloro-8-hydroxyquinoline Glucuronide
CAS No.: 65851-39-0
4,4'-Diaponeurosporene
CAS No.: 53872-50-7
info@thebiotek.com
256 N Vinedo Ave, Pasadena, California 91107
